7p2w: Difference between revisions
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==E.coli GyrB24 with inhibitor LMD92 (EBL2682)== | |||
<StructureSection load='7p2w' size='340' side='right'caption='[[7p2w]], [[Resolution|resolution]] 1.65Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7p2w]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7P2W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7P2W FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4QR:2-[[3,4-bis(chloranyl)-5-methyl-1H-pyrrol-2-yl]carbonylamino]-4-[(3-carboxyphenyl)methoxy]-1,3-benzothiazole-6-carboxylic+acid'>4QR</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7p2w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7p2w OCA], [https://pdbe.org/7p2w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7p2w RCSB], [https://www.ebi.ac.uk/pdbsum/7p2w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7p2w ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/GYRB_ECOLI GYRB_ECOLI] DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings.<ref>PMID:12051843</ref> <ref>PMID:18642932</ref> <ref>PMID:20675723</ref> | |||
==See Also== | |||
*[[Gyrase 3D Structures|Gyrase 3D Structures]] | |||
== References == | |||
[[Category: | <references/> | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli K-12]] | |||
[[Category: Large Structures]] | |||
[[Category: Durcik M]] | |||
[[Category: Henderson SR]] | |||
[[Category: Ilas J]] | |||
[[Category: Kikelj D]] | |||
[[Category: Lawson DM]] | |||
[[Category: Masic LP]] | |||
[[Category: Maxwell AM]] | |||
[[Category: Stevenson CEM]] | |||
[[Category: Tomasic T]] | |||
[[Category: Zega A]] | |||
[[Category: Zidar N]] | |||
Latest revision as of 11:07, 2 August 2023
E.coli GyrB24 with inhibitor LMD92 (EBL2682)
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