7p2x: Difference between revisions
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==E.coli GyrB24 with inhibitor KOB20 (EBL2583)== | |||
<StructureSection load='7p2x' size='340' side='right'caption='[[7p2x]], [[Resolution|resolution]] 1.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7p2x]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7P2X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7P2X FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4Q6:(2Z)-2-[[4,5-bis(bromanyl)-1H-pyrrol-2-yl]carbonylimino]-3-(phenylmethyl)-1,3-benzothiazole-6-carboxylic+acid'>4Q6</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7p2x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7p2x OCA], [https://pdbe.org/7p2x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7p2x RCSB], [https://www.ebi.ac.uk/pdbsum/7p2x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7p2x ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/GYRB_ECOLI GYRB_ECOLI] DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings.<ref>PMID:12051843</ref> <ref>PMID:18642932</ref> <ref>PMID:20675723</ref> | |||
==See Also== | |||
*[[Gyrase 3D Structures|Gyrase 3D Structures]] | |||
== References == | |||
[[Category: | <references/> | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli K-12]] | |||
[[Category: Large Structures]] | |||
[[Category: Benek O]] | |||
[[Category: Henderson SR]] | |||
[[Category: Ilas J]] | |||
[[Category: Kikelj D]] | |||
[[Category: Lawson DM]] | |||
[[Category: Masic LP]] | |||
[[Category: Maxwell AM]] | |||
[[Category: Stevenson CEM]] | |||
[[Category: Tomasic T]] | |||
[[Category: Zega A]] | |||
[[Category: Zidar N]] | |||
Latest revision as of 13:00, 1 February 2024
E.coli GyrB24 with inhibitor KOB20 (EBL2583)
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