7fi5: Difference between revisions
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==Crystal structure of human MICA mutants in complex with natural killer cell receptor NKG2D== | |||
<StructureSection load='7fi5' size='340' side='right'caption='[[7fi5]], [[Resolution|resolution]] 2.39Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7fi5]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FI5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FI5 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.39Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fi5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fi5 OCA], [https://pdbe.org/7fi5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fi5 RCSB], [https://www.ebi.ac.uk/pdbsum/7fi5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fi5 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/NKG2D_HUMAN NKG2D_HUMAN] Receptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes. | |||
==See Also== | |||
*[[NK cell receptor|NK cell receptor]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Cai W]] | |||
[[Category: Li Y]] | |||
[[Category: Liu J]] | |||
[[Category: Peng S]] | |||
[[Category: Tian Y]] | |||
[[Category: Xu T]] | |||
Latest revision as of 17:16, 29 November 2023
Crystal structure of human MICA mutants in complex with natural killer cell receptor NKG2D
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