7uzt: Difference between revisions
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New page: '''Unreleased structure''' The entry 7uzt is ON HOLD Authors: Description: Category: Unreleased Structures |
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==Crystal structure of the human astrovirus MLB1 capsid protein spike domain at 1.86-A resolution== | |||
<StructureSection load='7uzt' size='340' side='right'caption='[[7uzt]], [[Resolution|resolution]] 1.86Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7uzt]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Astrovirus_MLB1 Astrovirus MLB1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7UZT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7UZT FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.86Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7uzt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7uzt OCA], [https://pdbe.org/7uzt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7uzt RCSB], [https://www.ebi.ac.uk/pdbsum/7uzt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7uzt ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/B6UYJ1_9VIRU B6UYJ1_9VIRU] The capsid polyprotein VP90 self-assembles and undergoes a proteolytic cleavage by host caspases to yield the VP70 virions. This immature virion is composed of 180 VP70 subunits with 90 dimeric spikes and displays a T=3 icosahedral symmetry. The mature virion is obtained by further cleavages resulting in three structural proteins VP25, VP27 and VP34. This forms contains only 30 spikes located on the icosahedral 2-fold axes. Plays a role in the attachment to target host cell. This attachment induces virion internalization through clathrin-dependent endocytosis.[RuleBase:RU363102] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Astrovirus MLB1]] | |||
[[Category: Large Structures]] | |||
[[Category: Delgado-Cunningham K]] | |||
[[Category: DuBois R]] | |||
Latest revision as of 10:44, 22 May 2024
Crystal structure of the human astrovirus MLB1 capsid protein spike domain at 1.86-A resolution
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