6h7j: Difference between revisions

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<StructureSection load='6h7j' size='340' side='right'caption='[[6h7j]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='6h7j' size='340' side='right'caption='[[6h7j]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6h7j]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Camelus_glama Camelus glama], [https://en.wikipedia.org/wiki/Ecoli Ecoli] and [https://en.wikipedia.org/wiki/Melga Melga]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6H7J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6H7J FirstGlance]. <br>
<table><tr><td colspan='2'>[[6h7j]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12], [https://en.wikipedia.org/wiki/Lama_glama Lama glama] and [https://en.wikipedia.org/wiki/Meleagris_gallopavo Meleagris gallopavo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6H7J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6H7J FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2CV:HEGA-10'>2CV</scene>, <scene name='pdbligand=5FW:ISOPRENALINE'>5FW</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">trxA, fipA, tsnC, b3781, JW5856 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI]), ADRB1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9103 MELGA])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2CV:HEGA-10'>2CV</scene>, <scene name='pdbligand=5FW:ISOPRENALINE'>5FW</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6h7j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6h7j OCA], [https://pdbe.org/6h7j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6h7j RCSB], [https://www.ebi.ac.uk/pdbsum/6h7j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6h7j ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6h7j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6h7j OCA], [https://pdbe.org/6h7j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6h7j RCSB], [https://www.ebi.ac.uk/pdbsum/6h7j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6h7j ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/THIO_ECOLI THIO_ECOLI]] Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. [[https://www.uniprot.org/uniprot/ADRB1_MELGA ADRB1_MELGA]] Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity.  
[https://www.uniprot.org/uniprot/THIO_ECOLI THIO_ECOLI] Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Camelus glama]]
[[Category: Escherichia coli K-12]]
[[Category: Ecoli]]
[[Category: Lama glama]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Melga]]
[[Category: Meleagris gallopavo]]
[[Category: Dore, A S]]
[[Category: Dore AS]]
[[Category: Edwards, P C]]
[[Category: Edwards PC]]
[[Category: Leslie, A G.W]]
[[Category: Leslie AGW]]
[[Category: Tate, C G]]
[[Category: Tate CG]]
[[Category: Warne, T]]
[[Category: Warne T]]
[[Category: Activated]]
[[Category: Agonist]]
[[Category: Beta1 adrenoceptor]]
[[Category: Immune system]]
[[Category: Nanobody]]

Latest revision as of 12:43, 6 November 2024

ACTIVATED TURKEY BETA1 ADRENOCEPTOR WITH BOUND AGONIST ISOPRENALINE AND NANOBODY Nb80

6h7j, resolution 2.80Å

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