2lha: Difference between revisions
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==Solution structure of C2B with IP6== | ==Solution structure of C2B with IP6== | ||
<StructureSection load='2lha' size='340' side='right'caption='[[2lha | <StructureSection load='2lha' size='340' side='right'caption='[[2lha]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2lha]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2lha]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LHA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LHA FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IHP:INOSITOL+HEXAKISPHOSPHATE'>IHP</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lha FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lha OCA], [https://pdbe.org/2lha PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lha RCSB], [https://www.ebi.ac.uk/pdbsum/2lha PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lha ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lha FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lha OCA], [https://pdbe.org/2lha PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lha RCSB], [https://www.ebi.ac.uk/pdbsum/2lha PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lha ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/SYT1_HUMAN SYT1_HUMAN] May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2. | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Joung | [[Category: Joung M]] | ||
[[Category: Mohan | [[Category: Mohan SK]] | ||
[[Category: Yu | [[Category: Yu C]] | ||
Latest revision as of 05:43, 15 May 2024
Solution structure of C2B with IP6
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