3vqg: Difference between revisions
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<StructureSection load='3vqg' size='340' side='right'caption='[[3vqg]], [[Resolution|resolution]] 1.35Å' scene=''> | <StructureSection load='3vqg' size='340' side='right'caption='[[3vqg]], [[Resolution|resolution]] 1.35Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3vqg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[3vqg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VQG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VQG FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.35Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vqg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vqg OCA], [https://pdbe.org/3vqg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vqg RCSB], [https://www.ebi.ac.uk/pdbsum/3vqg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vqg ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vqg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vqg OCA], [https://pdbe.org/3vqg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vqg RCSB], [https://www.ebi.ac.uk/pdbsum/3vqg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vqg ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/LNX1_MOUSE LNX1_MOUSE] E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65. Isoform 2 provides an endocytic scaffold for IGSF5/JAM4. | |||
==See Also== | ==See Also== | ||
*[[Ubiquitin protein ligase 3D structures|Ubiquitin protein ligase 3D structures]] | *[[Ubiquitin protein ligase 3D structures|Ubiquitin protein ligase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Mus musculus]] | ||
[[Category: Akiyoshi | [[Category: Akiyoshi Y]] | ||
[[Category: Furuse | [[Category: Furuse M]] | ||
[[Category: Goda | [[Category: Goda N]] | ||
[[Category: Hamada | [[Category: Hamada D]] | ||
[[Category: Hiroaki | [[Category: Hiroaki H]] | ||
[[Category: Nakagawa | [[Category: Nakagawa A]] | ||
[[Category: Narita | [[Category: Narita H]] | ||
[[Category: Suzuki | [[Category: Suzuki M]] | ||
[[Category: Tenno | [[Category: Tenno T]] | ||
Latest revision as of 12:33, 8 November 2023
Crystal Structure Analysis of the PDZ Domain Derived from the Tight Junction Regulating Protein
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