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==Crystal structure of class II pyruvate aldolase from Pseudomonas aeruginosa.==
==Crystal structure of class II pyruvate aldolase from Pseudomonas aeruginosa.==
<StructureSection load='7v8t' size='340' side='right'caption='[[7v8t]]' scene=''>
<StructureSection load='7v8t' size='340' side='right'caption='[[7v8t]], [[Resolution|resolution]] 2.48&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7V8T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7V8T FirstGlance]. <br>
<table><tr><td colspan='2'>[[7v8t]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7V8T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7V8T FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7v8t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7v8t OCA], [https://pdbe.org/7v8t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7v8t RCSB], [https://www.ebi.ac.uk/pdbsum/7v8t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7v8t ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.48&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7v8t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7v8t OCA], [https://pdbe.org/7v8t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7v8t RCSB], [https://www.ebi.ac.uk/pdbsum/7v8t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7v8t ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HPAAL_PSEAI HPAAL_PSEAI] Aldolase which can catalyze in vitro the aldolisation reaction between hydroxypyruvate (HPA) or pyruvate (PA) and D-glyceraldehyde (D-GA) (Ref.1). The condensation of hydroxypyruvate and D-glyceraldehyde produces (3R,4S,5R)-3,4,5,6-tetrahydroxy-2-oxohexanoate as the major product, 2-dehydro-D-gluconate and 2-dehydro-D-galactonate (Ref.1). The condensation of pyruvate and D-glyceraldehyde produces 2-dehydro-3-deoxy-L-galactonate as the major product and 2-dehydro-3-deoxy-D-gluconate (Ref.1). Also catalyzes the retro-aldol type decarboxylation of oxaloacetate, a general property of known pyruvate aldolases (Ref.1).[UniProtKB:Q47098]
==See Also==
*[[Aldolase 3D structures|Aldolase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Kim JS]]
[[Category: Kim JS]]
[[Category: Seo PW]]
[[Category: Seo PW]]

Latest revision as of 11:44, 30 October 2024

Crystal structure of class II pyruvate aldolase from Pseudomonas aeruginosa.

7v8t, resolution 2.48Å

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