Polycomb complex proteins 3D structures: Difference between revisions

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New page: ==3D structures of polycomb complex proteins== Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| * Polycomb group ri...
 
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==3D structures of polycomb complex proteins==
==3D structures of polycomb complex proteins==


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{{#tree:id=OrganizedByTopic|openlevels=0|
{{#tree:id=OrganizedByTopic|openlevels=0|


* Polycomb group ring finger protein 1 or Pcgf1
*Polycomb group ring finger protein 1 or Pcgf1


**[[4hpm]] – hPcgf1 167-255 + BCORL1 - human<br />
**[[4hpm]] – hPcgf1 167-255 + BCORL1 - human<br />
**[[4hpl]] – hPcgf1 167-255 + BCOR<br />
**[[4hpl]] – hPcgf1 + BCOR<br />
**[[8hcu]] – hPcgf1 + BCOR + JMJC domain-containing histon demethylation protein<br />
**[[5jh5]] – hPcgf1 + lysine-specific demethylase + S-phase kinase associated protein 1<br />
 
*BMI-1 or Polycomb group ring finger protein 4 or Pcgf4


* BMI-1 or Polycomb group ring finger protein 4 or Pcgf4
**[[5fr6]] – hBMI1 residues 121-235 <br />
**[[5fr6]] – hBMI1 residues 121-235 <br />
**[[2na1]] – hBMI1 residues 121-235 /polyhomeotic-like 2– NMR<br />
**[[2na1]] – hBMI1 residues 121-235 /polyhomeotic-like 2– NMR<br />
**[[6wi7]], [[6wi8]] – hBMI1 residues 1-104 /RING1B <br />
**[[6wi7]], [[8wi8]] – hBMI1 ring domain 1-108/Ring1B <br />
**[[6wi7]], [[8wi8]] – hBMI1 ring domain 1-108/Ring1B <br />
**[[7nd1]] – hBMI1 ring domain + Ring1B - NMR<br />
**[[7nd1]] – hBMI1 ring domain + Ring1B - NMR<br />
**[[3rpg]] – hBMI1 ring domain + Ring1B + Ubch5C<br />
**[[3rpg]] – hBMI1 ring domain + Ring1B + Ubch5C<br />
**[[9dby]], [[9dgg]] – hBMI1 + nucleosome – Cryo EM<br />
**[[9dde]] – hBMI1 + chromatosome – Cryo EM<br />
**[[8pp7]] – hBMI1 + RING2 + nucleosome – Cryo EM<br />
**[[2ckl]] – mBMI1 ring domain + Ring1B - mouse<br />
**[[2ckl]] – mBMI1 ring domain + Ring1B - mouse<br />
**[[4r8p]] – BMI1 ring domain + Ring1B + Ubch5C + DNA - frog<br />
**[[4r8p]] – BMI1 ring domain + Ring1B + Ubch5C + DNA - frog<br />
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*Polycomb EED
*Polycomb EED


**[[5wf7]], [[5bjs]], [[5vk3]] - CtPcG + EZH2/PcG SUZ12 -  ''Chaetomium thermophilum''<br />
**[[3jpx]], [[3iiw]], [[3iiy]], [[3ij0]], [[3ij1]], [[3jzg]], [[3jzh]], [[3jzn]], [[5fr6]], [[7kxt]] - hPcG <br />
**[[5wfd]] - CtPcG + zinc finger containing protein + inhibitor<br />
**[[5u69]], [[5u6d]], [[5u8a]], [[5k0m]], [[5h13]], [[5u5h]], [[5u5k]], [[5u8f]], [[6sfb]], [[6sfc]], [[6w7f]], [[6w7g]], [[6yvi]], [[6yvj]], [[7msb]], [[7msd]], [[7p3c]], [[7p3g]], [[7p3j]], [[7qjg]], [[7qju]], [[7qk4]], [[7si4]], [[7si5]] - hPcG + inhibitor <br />
**[[5wfc]] - CtPcG (mutant) + EZH2/PcG SUZ12 + histone peptide + inhibitor<br />
**[[5tqr]] - CtPcGCP + EZH2/PCP SUZ12 + SAM<br />
**[[3jzn]] - hPcG  <br />
**[[5wg6]] - hPcG + EZH2 <br />
**[[5ij7]], [[5ij8]], [[4w2r]], [[6b3w]] - hPcG + EZH2 + PcG SUZ12  + inhibitor<br />
**[[5ij8]] - hPcG + EZH2 + PcG SUZ12  + inhibitor<br />
**[[5ls6]] - hPcG + EZH2 + PcG SUZ12 + Jarid2 K116me3 <br />
**[[5hyn]] - hPcG + EZH2 + PcG SUZ12 + Jarid2 K116me3 + histone peptide<br />
**[[6c23]], [[6c24]] - hPcG + EZH2 + PcG SUZ12 + Jarid2 substrate + Jumonji + SUZ12 + RBBP4 - Cryo EM<br />
**[[4x3e]] - hPcG + Jarid2 peptide <br />
**[[3jpx]], [[3iiw]], [[3iiy]], [[3ij0]], [[3ij1]], [[3jzg]], [[3jzh]], [[3k26]],[[5fr6]] - hPcG <br />
**[[5u69]], [[5u6d]], [[5u8a]], [[5k0m]], [[5h13]], [[5u5h]], [[5u5k]], [[5u8f]] - hPcG + inhibitor <br />
**[[3ijc]] - hPcG (mutant) + inhibitor <br />
**[[3ijc]] - hPcG (mutant) + inhibitor <br />
**[[6v3x]], [[6v3y]] - hPcG + PALI1 peptide<br />
**[[3k26]], [[3k27]] - hPcG + histone peptide<br />
**[[5wp3]] - hPcG + EB22 <br />
**[[5wp3]] - hPcG + EB22 <br />
**[[5ttw]] - hPcG + UNC4859 <br />
**[[5ttw]] - hPcG + UNC4859 <br />
**[[5h14]], [[5h15]], [[5h17]], [[5h19]], [[5u5t]], [[5u62]], [[5h25]], [[5gsa]], [[5h24]], [[5wuk]] - hPcG + EZH2 + inhibitor <br />
**[[5gsa]], [[5h14]], [[5h15]], [[5h17]], [[5h19]], [[5h24]], [[5h25]], [[5u5t]], [[5u62]], [[5wuk]], [[6lo2]] - hPcG + EZH2 peptide + inhibitor <br />
**[[5wg6]], [[6u4y]] - hPcG + EZH2 <br />
**[[7ktp]] - hPcG + ENX-2 + PcG SUZ12 + RBBP4 - Cryo EM<br />
**[[7td5]] - hPcG + ENX-2 + PcG SUZ12 + peptide<br />
**[[4x3e]] - hPcG + Jarid2 peptide <br />
**[[1pdq]], [[1pfb]] - DmPcG chromodomain + histone peptide - ''Drosophila melanogaster''<br />
**[[1pdq]], [[1pfb]] - DmPcG chromodomain + histone peptide - ''Drosophila melanogaster''<br />
**[[5wf7]] - CtPcG + PcG SUZ12 -  ''Chaetomium thermophilum''<br />
**[[5bjs]], [[5vk3]] - CtPcG + EZH2 <br />
**[[5wfd]] - CtPcG + zinc finger containing protein + inhibitor<br />


*Polycomb SUZ12
*Polycomb SUZ12
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**[[5wak]] - hPcG + RBBP4 <br />
**[[5wak]] - hPcG + RBBP4 <br />
**[[5wai]] - hPcG + RBBP4 + Jarid2 + AEPB2 <br />
**[[5wai]] - hPcG + RBBP4 + Jarid2 + AEPB2 <br />
**[[6nq3]] - hPcG + RBBP4 + Jumonji + Phd finger protein <br />
**[[7at8]] - hPcG + EZH2 + nucleosome – Cryo EM<br />
**[[2yb8]] - DmPcG + CAF1<br />
**[[2yb8]] - DmPcG + CAF1<br />
*Polycomb EED+ polycomb EED in polycomb repressive complex 2 PCR2
**[[5w2r]], [[5ij7]], [[5ij8]], [[6b3w]] – hPCR2 + inhibitor<br />
**[[5ls6]] – hPCR2 + Jarid2 K116me3 <br />
**[[5hyn]] – hPCR2 + Jarid2 K116me3 + histone peptide<br />
**[[6c23]], [[6c24]] – hPCR2 + RBBP4 + AEBP2 + Jumonji + SUZ12 + JARID2 - Cryo EM<br />
**[[7kso]], [[8vnz]], [[9c8u]] – hPCR2 + RBBP4 + AEBP2 + Jumonji - Cryo EM<br />
**[[6wkr]] – hPCR2 + RBBP4 + AEBP2 + Jumonji + Ub + nucleosome - Cryo EM<br />
**[[8t9g]] – hPCR2 + RBBP4 + AEBP2 + SAH + nucleosome - Cryo EM<br />
**[[8tb9]] – hPCR2 + RBBP4 + AEBP2 + Jumonji + SAH + nucleosome - Cryo EM<br />
**[[8tas]] – hPCR2 + RBBP4 + AEBP2 + nucleosome - Cryo EM<br />
**[[8eqv]] – hPCR2 + RBBP4 + AEBP2 - Cryo EM<br />
**[[7ksr]] – hPCR2 + RBBP4 - Cryo EM<br />
**[[8vmi]] – hPCR2 + RBPP4 + Jumonji + AEPB2 + histone - Cryo EM<br />
**[[8vnv]] – hPCR2 + RBPP4 + Jumonji + AEPB2 + histone + DNA - Cryo EM<br />
**[[8fyh]], [[9dch]] – hPCR2 + RBPP4 + Jumonji + AEPB2 + RNA - Cryo EM<br />
**[[5wfc]] – CtPCR2 + histone peptide + inhibitor<br />
**[[5tqr]] – PCR2 + SAM<br />


*Polycomb SCMH1
*Polycomb SCMH1
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**[[2r5m]] - DmPcG (mutant) + peptide <br />
**[[2r5m]] - DmPcG (mutant) + peptide <br />


*Polycomb ASX
**[[8svf]] – hAsXL1 + BAP1 + nucleosome – Cryo EM<br />
**[[9u5u]] – hAsXL1 + BAP1 + Ub + nucleosome – Cryo EM<br />
**[[9atn]] – hAsXL2 652-670 + histone lysine N-methyltransferase – NMR<br />
**[[6cga]], [[6hgc]] - DmAsX 207-340 + calypso <br />
**[[9v33]] - DmAsX 1-340 + calypso + Ub + nucleosome – Cryo EM<br />
**[[8h1t]] – DmAsXL1 + BAP1 + chromatosome – Cryo EM<br />
*Polycomb-like protein 1 or PHD finger protein 1 or HPCL1
**[[6wat]] – hPcL1 <br />
**[[5xfn]], [[5xfo]] – hPcL1 N-terminal 25-340 <br />
**[[5xfp]] – hPcL1 N-terminal + DNA<br />
**[[5xfq]] – hPcL1 25-360 + histone 3 + DNA<br />
**[[2m0o]], [[4hcz]], [[6wau]], [[6wav]] – hPcL1 TUDOR domain 28-87 + histone 3.1<br />
**[[4bd3]] – hPcL3 TUDOR domain + histone 3<br />
**[[6nq3]] – hPcL3 500-580 + SUZ12 + RBBP4 + Jumonji<br />
**[[7lky]] – hPcL1 TUDOR domain + peptide inhibitor<br />
**[[5oqd]] – DmPcL WINGED-HELIX domain 491-694<br />
}}
[[Category:Topic Page]]
[[Category:Topic Page]]
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