8foc: Difference between revisions
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New page: '''Unreleased structure''' The entry 8foc is ON HOLD Authors: Description: Category: Unreleased Structures |
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==Cryo-EM structure of S. cerevisiae DNA polymerase alpha-primase in Apo state conformation I== | |||
<StructureSection load='8foc' size='340' side='right'caption='[[8foc]], [[Resolution|resolution]] 3.70Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8foc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8FOC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8FOC FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.7Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8foc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8foc OCA], [https://pdbe.org/8foc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8foc RCSB], [https://www.ebi.ac.uk/pdbsum/8foc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8foc ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/PRI2_YEAST PRI2_YEAST] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. In a complex with DNA polymerase alpha (DNA polymerase alpha:primase) constitutes a replicative polymerase. Both primase components participate in formation of the active center, but the ATP-binding site is exclusively located on p48. | |||
==See Also== | |||
*[[RNA polymerase 3D structures|RNA polymerase 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Saccharomyces cerevisiae]] | |||
[[Category: Georgescu R]] | |||
[[Category: Li H]] | |||
[[Category: O'Donnell M]] | |||
[[Category: Yuan Z]] | |||
Latest revision as of 15:16, 13 August 2026
Cryo-EM structure of S. cerevisiae DNA polymerase alpha-primase in Apo state conformation I
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