8uh0: Difference between revisions
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New page: '''Unreleased structure''' The entry 8uh0 is ON HOLD Authors: Description: Category: Unreleased Structures |
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The entry | ==SOS2 co-crystal structure with fragment bound (compound 10)== | ||
<StructureSection load='8uh0' size='340' side='right'caption='[[8uh0]], [[Resolution|resolution]] 2.73Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8uh0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8UH0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8UH0 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.73Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=WRN:8-hydroxyquinoline-2-carbonitrile'>WRN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8uh0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8uh0 OCA], [https://pdbe.org/8uh0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8uh0 RCSB], [https://www.ebi.ac.uk/pdbsum/8uh0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8uh0 ProSAT]</span></td></tr> | |||
</table> | |||
== Disease == | |||
[https://www.uniprot.org/uniprot/SOS2_HUMAN SOS2_HUMAN] Noonan syndrome. The disease is caused by mutations affecting the gene represented in this entry. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/SOS2_HUMAN SOS2_HUMAN] Promotes the exchange of Ras-bound GDP by GTP.[UniProtKB:Q62245] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Gunn RJ]] | |||
[[Category: Lawson JD]] | |||
Latest revision as of 15:05, 13 March 2024
SOS2 co-crystal structure with fragment bound (compound 10)
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