1x5m: Difference between revisions
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New page: left|200px<br /> <applet load="1x5m" size="450" color="white" frame="true" align="right" spinBox="true" caption="1x5m" /> '''Solution structure of the core domain of ca... |
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== | ==Solution structure of the core domain of calcyclin binding protein; siah-interacting protein (SIP)== | ||
<StructureSection load='1x5m' size='340' side='right'caption='[[1x5m]]' scene=''> | |||
== Structural highlights == | |||
== | <table><tr><td colspan='2'>[[1x5m]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X5M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1X5M FirstGlance]. <br> | ||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1x5m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x5m OCA], [https://pdbe.org/1x5m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1x5m RCSB], [https://www.ebi.ac.uk/pdbsum/1x5m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1x5m ProSAT], [https://www.topsan.org/Proteins/RSGI/1x5m TOPSAN]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/CYBP_HUMAN CYBP_HUMAN] May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1).<ref>PMID:16085652</ref> | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x5/1x5m_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1x5m ConSurf]. | |||
<div style="clear:both"></div> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Hayashi | [[Category: Hayashi F]] | ||
[[Category: Nagashima | [[Category: Nagashima T]] | ||
[[Category: Qin | [[Category: Qin XR]] | ||
[[Category: Yokoyama S]] | |||
[[Category: Yokoyama | |||
Latest revision as of 14:00, 9 May 2024
Solution structure of the core domain of calcyclin binding protein; siah-interacting protein (SIP)
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