9m65: Difference between revisions
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New page: '''Unreleased structure''' The entry 9m65 is ON HOLD Authors: Xia, Y.Q., Liu, L., Zhang, Q., Shi, X.C., Wang, Z.K., Zhang, Z.C., He, X.Y., Xiao, J.H., Jiang, H.B., Zhang, S.C., Yang, Y.... |
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==Crystal structure of the pathogen-secreted apoplastic GH12 xyloglucan-specific endoglucanase XEG1== | |||
<StructureSection load='9m65' size='340' side='right'caption='[[9m65]], [[Resolution|resolution]] 2.59Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9m65]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Phytophthora_sojae_strain_P6497 Phytophthora sojae strain P6497]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9M65 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9M65 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.59Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1ENU:~{N}-(4-ethoxyphenyl)-4-[(10~{R},15~{S})-10-(4-methylphenyl)-12,14-bis(oxidanylidene)-8,11,13-triazatetracyclo[7.7.0.0^{2,7}.0^{11,15}]hexadeca-1(9),2,4,6-tetraen-13-yl]benzamide'>A1ENU</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9m65 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9m65 OCA], [https://pdbe.org/9m65 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9m65 RCSB], [https://www.ebi.ac.uk/pdbsum/9m65 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9m65 ProSAT]</span></td></tr> | ||
[[Category: He | </table> | ||
[[Category: Liu | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/XEG1_PHYSP XEG1_PHYSP] Glycoside hydrolase that exhibits xyloglucanase activity (PubMed:26163574). Acts as an important virulence factor during P.sojae infection but also acts as a pathogen-associated molecular pattern (PAMP) in soybean and solanaceous species, where it can trigger defense responses including cell death. XEG1-induced cell death can be suppressed by P.sojae RxLR effectors. The PAMP activity is independent of its xyloglucanase activity (PubMed:26163574). XEG1 induces plant defense responses in a RLP kinase Serk3/Bak1-dependent manner in Nicotiana benthamiana. Moreover, the perception of XEG1 occurs independently of the perception of ethylene-inducing xylanase Eix2 in Tomato (PubMed:26163574). With truncated paralog XLP1, is required to elevate apoplastic sugar during P.sojae infection (PubMed:28082413).<ref>PMID:26163574</ref> <ref>PMID:28082413</ref> | ||
[[Category: | == References == | ||
[[Category: | <references/> | ||
[[Category: Wang | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Phytophthora sojae strain P6497]] | ||
[[Category: | [[Category: He XY]] | ||
[[Category: | [[Category: Jiang HB]] | ||
[[Category: | [[Category: Liu L]] | ||
[[Category: | [[Category: Ma ZC]] | ||
[[Category: | [[Category: Shi XC]] | ||
[[Category: | [[Category: Wang Y]] | ||
[[Category: Zhang | [[Category: Wang YC]] | ||
[[Category: Wang ZK]] | |||
[[Category: Wang ZY]] | |||
[[Category: Xia YQ]] | |||
[[Category: Xiao JH]] | |||
[[Category: Yang Q]] | |||
[[Category: Yang YH]] | |||
[[Category: Ye WW]] | |||
[[Category: Zhang Q]] | |||
[[Category: Zhang SC]] | |||
[[Category: Zhang ZC]] | |||
Latest revision as of 07:31, 19 March 2026
Crystal structure of the pathogen-secreted apoplastic GH12 xyloglucan-specific endoglucanase XEG1
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