9u3p: Difference between revisions
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New page: '''Unreleased structure''' The entry 9u3p is ON HOLD Authors: Description: Category: Unreleased Structures |
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==Cryo-EM structure of human AC9-Gs complex (soluble domain)== | |||
<StructureSection load='9u3p' size='340' side='right'caption='[[9u3p]], [[Resolution|resolution]] 2.65Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9u3p]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Human_orthopneumovirus Human orthopneumovirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9U3P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9U3P FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.65Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GSP:5-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE'>GSP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9u3p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9u3p OCA], [https://pdbe.org/9u3p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9u3p RCSB], [https://www.ebi.ac.uk/pdbsum/9u3p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9u3p ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ADCY9_HUMAN ADCY9_HUMAN] Adenylyl cyclase that catalyzes the formation of the signaling molecule cAMP in response to activation of G protein-coupled receptors (PubMed:10987815, PubMed:12972952, PubMed:15879435, PubMed:9628827). Contributes to signaling cascades activated by CRH (corticotropin-releasing factor), corticosteroids and beta-adrenergic receptors (PubMed:9628827).<ref>PMID:10987815</ref> <ref>PMID:12972952</ref> <ref>PMID:15879435</ref> <ref>PMID:9628827</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Human orthopneumovirus]] | |||
[[Category: Large Structures]] | |||
[[Category: Fujiyoshi Y]] | |||
[[Category: Nishikawa K]] | |||
[[Category: Nomura R]] | |||
[[Category: Suzuki H]] | |||
[[Category: Suzuki S]] | |||