9yp4: Difference between revisions
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New page: '''Unreleased structure''' The entry 9yp4 is ON HOLD Authors: Somavarapu, A.K., Craig, R., Padron, R. Description: Cryo-EM structure of human beta-cardiac myosin bound to omecamtiv mec... |
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==Cryo-EM structure of human beta-cardiac myosin bound to omecamtiv mecarbil in the interacting-heads motif and S2-FH docked state== | |||
<StructureSection load='9yp4' size='340' side='right'caption='[[9yp4]], [[Resolution|resolution]] 4.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9yp4]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Aequorea_victoria Aequorea victoria], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9YP4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9YP4 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.5Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2OW:METHYL+4-(2-FLUORO-3-{[(6-METHYLPYRIDIN-3-YL)CARBAMOYL]AMINO}BENZYL)PIPERAZINE-1-CARBOXYLATE'>2OW</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9yp4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9yp4 OCA], [https://pdbe.org/9yp4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9yp4 RCSB], [https://www.ebi.ac.uk/pdbsum/9yp4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9yp4 ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: Craig | == Function == | ||
[https://www.uniprot.org/uniprot/MYL11_MOUSE MYL11_MOUSE] Myosin regulatory subunit that plays an essential role to maintain muscle integrity during early development (PubMed:17356007). Plays a role in regulation of muscle contraction (By similarity).[UniProtKB:O93409]<ref>PMID:17356007</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Aequorea victoria]] | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Mus musculus]] | |||
[[Category: Saccharomyces cerevisiae]] | |||
[[Category: Craig R]] | |||
[[Category: Padron R]] | |||
[[Category: Somavarapu AK]] | |||
Latest revision as of 06:37, 8 April 2026
Cryo-EM structure of human beta-cardiac myosin bound to omecamtiv mecarbil in the interacting-heads motif and S2-FH docked state
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