1xhc: Difference between revisions

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[[Image:1xhc.jpg|left|200px]]


<!--
==NADH oxidase /nitrite reductase from Pyrococcus furiosus Pfu-1140779-001==
The line below this paragraph, containing "STRUCTURE_1xhc", creates the "Structure Box" on the page.
<StructureSection load='1xhc' size='340' side='right'caption='[[1xhc]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1xhc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus_DSM_3638 Pyrococcus furiosus DSM 3638]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XHC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XHC FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
{{STRUCTURE_1xhc|  PDB=1xhc  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xhc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xhc OCA], [https://pdbe.org/1xhc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xhc RCSB], [https://www.ebi.ac.uk/pdbsum/1xhc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xhc ProSAT]</span></td></tr>
 
</table>
'''NADH oxidase /nitrite reductase from Pyrococcus furiosus Pfu-1140779-001'''
== Function ==
 
[https://www.uniprot.org/uniprot/NROR_PYRFU NROR_PYRFU] Catalyzes the NADH-dependent reduction of rubredoxin (Rd), a small iron-containing redox protein (PubMed:10464233, PubMed:11398485, PubMed:15746356). Can also reduce other electron carriers, including 2,6-dichlorophenol indophenol, benzyl viologen and menadione, but rubredoxin is the most efficient electron acceptor (PubMed:10464233, PubMed:11398485, PubMed:15746356). Does not reduce ferredoxin (PubMed:10464233). Shows comparable activity with NADPH and NADH as electron donors, but NADPH is probably the preferred physiological electron donor (PubMed:10464233, PubMed:11398485). Is probably part of an oxygen detoxification system that protects P.furiosus during exposure to oxygen (PubMed:15746356).<ref>PMID:10464233</ref> <ref>PMID:11398485</ref> <ref>PMID:15746356</ref>
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
1XHC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus_dsm_3638 Pyrococcus furiosus dsm 3638]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XHC OCA].  
Check<jmol>
[[Category: Pyrococcus furiosus dsm 3638]]
  <jmolCheckbox>
[[Category: Single protein]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xh/1xhc_consurf.spt"</scriptWhenChecked>
[[Category: Adams, M W.W.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Brereton, P S.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Chen, L.]]
  </jmolCheckbox>
[[Category: Horanyi, P.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xhc ConSurf].
[[Category: II, F L.Poole.]]
<div style="clear:both"></div>
[[Category: III, W B.Arendall.]]
== References ==
[[Category: Izumi, M.]]
<references/>
[[Category: Jr., F E.Jenney.]]
__TOC__
[[Category: Lee, D.]]
</StructureSection>
[[Category: Liu, Z J.]]
[[Category: Large Structures]]
[[Category: Richardson, D C.]]
[[Category: Pyrococcus furiosus DSM 3638]]
[[Category: Richardson, J S.]]
[[Category: Adams MWW]]
[[Category: Rose, J P.]]
[[Category: Arendall III WB]]
[[Category: SECSG, Southeast Collaboratory for Structural Genomics.]]
[[Category: Brereton PS]]
[[Category: Shah, A.]]
[[Category: Chen L]]
[[Category: Shah, C.]]
[[Category: Horanyi P]]
[[Category: Sugar, F J.]]
[[Category: Izumi M]]
[[Category: Tempel, W.]]
[[Category: Jenney Jr FE]]
[[Category: Wang, B C.]]
[[Category: Lee D]]
[[Category: Weinberg, M V.]]
[[Category: Liu Z-J]]
[[Category: Hyperthermophile]]
[[Category: Poole II FL]]
[[Category: Nadh oxidase]]
[[Category: Richardson DC]]
[[Category: Nitrite reductase]]
[[Category: Richardson JS]]
[[Category: Protein structure initiative]]
[[Category: Rose JP]]
[[Category: Psi]]
[[Category: Shah A]]
[[Category: Pyrococcus furiosus]]
[[Category: Shah C]]
[[Category: Secsg]]
[[Category: Sugar FJ]]
[[Category: Southeast collaboratory for structural genomic]]
[[Category: Tempel W]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 15:01:57 2008''
[[Category: Wang B-C]]
[[Category: Weinberg MV]]
Retrieved from "https://proteopedia.org/1xhc"