2o52: Difference between revisions

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New page: left|200px<br /> <applet load="2o52" size="450" color="white" frame="true" align="right" spinBox="true" caption="2o52, resolution 2.200Å" /> '''Crystal structure ...
 
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[[Image:2o52.gif|left|200px]]<br />
<applet load="2o52" size="450" color="white" frame="true" align="right" spinBox="true"
caption="2o52, resolution 2.200&Aring;" />
'''Crystal structure of human RAB4B in complex with GDP'''<br />


==About this Structure==
==Crystal structure of human RAB4B in complex with GDP==
2O52 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with MG, GDP, BME and UNX as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2O52 OCA].  
<StructureSection load='2o52' size='340' side='right'caption='[[2o52]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2o52]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O52 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2O52 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2o52 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o52 OCA], [https://pdbe.org/2o52 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2o52 RCSB], [https://www.ebi.ac.uk/pdbsum/2o52 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2o52 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RAB4B_HUMAN RAB4B_HUMAN] Protein transport. Probably involved in vesicular traffic (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o5/2o52_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2o52 ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Ras-related protein Rab 3D structures|Ras-related protein Rab 3D structures]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Arrowsmith, C.H.]]
[[Category: Arrowsmith CH]]
[[Category: Bochkarev, A.]]
[[Category: Bochkarev A]]
[[Category: Edwards, A.M.]]
[[Category: Edwards AM]]
[[Category: Landry, R.]]
[[Category: Landry R]]
[[Category: Park, H.]]
[[Category: Park H]]
[[Category: SGC, Structural.Genomics.Consortium.]]
[[Category: Shen Y]]
[[Category: Shen, Y.]]
[[Category: Sundstrom M]]
[[Category: Sundstrom, M.]]
[[Category: Tempel W]]
[[Category: Tempel, W.]]
[[Category: Wang J]]
[[Category: Wang, J.]]
[[Category: Weigelt J]]
[[Category: Weigelt, J.]]
[[Category: Zhu H]]
[[Category: Zhu, H.]]
[[Category: BME]]
[[Category: GDP]]
[[Category: MG]]
[[Category: UNX]]
[[Category: g-protein]]
[[Category: gdp]]
[[Category: rab]]
[[Category: sgc]]
[[Category: structural genomics]]
[[Category: structural genomics consortium]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Nov 12 23:06:49 2007''

Latest revision as of 10:30, 30 August 2023

Crystal structure of human RAB4B in complex with GDP

2o52, resolution 2.20Å

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