2pny: Difference between revisions
From Proteopedia
Jump to navigationJump to search
New page: left|200px<br /> <applet load="2pny" size="450" color="white" frame="true" align="right" spinBox="true" caption="2pny, resolution 1.81Å" /> '''Structure of Human ... |
No edit summary |
||
| (14 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
== | ==Structure of Human Isopentenyl-diphosphate Delta-isomerase 2== | ||
<StructureSection load='2pny' size='340' side='right'caption='[[2pny]], [[Resolution|resolution]] 1.81Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2pny]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PNY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PNY FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.81Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pny FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pny OCA], [https://pdbe.org/2pny PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pny RCSB], [https://www.ebi.ac.uk/pdbsum/2pny PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pny ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/IDI2_HUMAN IDI2_HUMAN] Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pn/2pny_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pny ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | |||
*[[Isopentenyl-diphosphate delta-isomerase|Isopentenyl-diphosphate delta-isomerase]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Arrowsmith CH]] | |||
[[Category: Arrowsmith | [[Category: Bochkarev A]] | ||
[[Category: Bochkarev | [[Category: Butler-Cole C]] | ||
[[Category: Butler-Cole | [[Category: Davis T]] | ||
[[Category: Davis | [[Category: Dhe-Paganon S]] | ||
[[Category: Dhe-Paganon | [[Category: Edwards AM]] | ||
[[Category: Edwards | [[Category: Sundstrom M]] | ||
[[Category: Walker JR]] | |||
[[Category: Sundstrom | [[Category: Weigelt J]] | ||
[[Category: Walker | |||
[[Category: Weigelt | |||
Latest revision as of 11:05, 30 August 2023
Structure of Human Isopentenyl-diphosphate Delta-isomerase 2
| ||||||||||||
