1su4: Difference between revisions
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New page: left|200px<br /> <applet load="1su4" size="450" color="white" frame="true" align="right" spinBox="true" caption="1su4, resolution 2.40Å" /> '''Crystal structure o... |
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== | ==Crystal structure of calcium ATPase with two bound calcium ions== | ||
<StructureSection load='1su4' size='340' side='right'caption='[[1su4]], [[Resolution|resolution]] 2.40Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[1su4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1eul 1eul]. The March 2004 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''The Calcium Pump'' by David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2004_3 10.2210/rcsb_pdb/mom_2004_3]. The October 2009 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Sodium-Potassium Pump'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2009_10 10.2210/rcsb_pdb/mom_2009_10]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SU4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SU4 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1su4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1su4 OCA], [https://pdbe.org/1su4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1su4 RCSB], [https://www.ebi.ac.uk/pdbsum/1su4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1su4 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/AT2A1_RABIT AT2A1_RABIT] This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction (By similarity). | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/su/1su4_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1su4 ConSurf]. | |||
<div style="clear:both"></div> | |||
== | ==See Also== | ||
*[[ATPase 3D structures|ATPase 3D structures]] | |||
[[Category: | __TOC__ | ||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Oryctolagus cuniculus]] | [[Category: Oryctolagus cuniculus]] | ||
[[Category: | [[Category: RCSB PDB Molecule of the Month]] | ||
[[Category: Sodium-Potassium Pump]] | |||
[[Category: The Calcium Pump]] | [[Category: The Calcium Pump]] | ||
[[Category: Nakasako | [[Category: Nakasako M]] | ||
[[Category: Nomura | [[Category: Nomura H]] | ||
[[Category: Ogawa | [[Category: Ogawa H]] | ||
[[Category: Toyoshima | [[Category: Toyoshima C]] | ||
Latest revision as of 08:35, 1 May 2024
Crystal structure of calcium ATPase with two bound calcium ions
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