1fip: Difference between revisions

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{{Seed}}
[[Image:1fip.png|left|200px]]


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==THE STRUCTURE OF FIS MUTANT PRO61ALA ILLUSTRATES THAT THE KINK WITHIN THE LONG ALPHA-HELIX IS NOT DUE TO THE PRESENCE OF THE PROLINE RESIDUE==
The line below this paragraph, containing "STRUCTURE_1fip", creates the "Structure Box" on the page.
<StructureSection load='1fip' size='340' side='right'caption='[[1fip]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1fip]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FIP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FIP FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fip FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fip OCA], [https://pdbe.org/1fip PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fip RCSB], [https://www.ebi.ac.uk/pdbsum/1fip PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fip ProSAT]</span></td></tr>
{{STRUCTURE_1fip| PDB=1fip |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/FIS_ECOLI FIS_ECOLI] Activates ribosomal RNA transcription, as well other genes. Plays a direct role in upstream activation of rRNA promoters. Binds to a recombinational enhancer sequence that is required to stimulate hin-mediated DNA inversion. Prevents initiation of DNA replication from oriC.<ref>PMID:2209559</ref> <ref>PMID:8836178</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fi/1fip_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fip ConSurf].
<div style="clear:both"></div>


===THE STRUCTURE OF FIS MUTANT PRO61ALA ILLUSTRATES THAT THE KINK WITHIN THE LONG ALPHA-HELIX IS NOT DUE TO THE PRESENCE OF THE PROLINE RESIDUE===
==See Also==
 
*[[FIS protein|FIS protein]]
 
== References ==
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<references/>
The line below this paragraph, {{ABSTRACT_PUBMED_7961857}}, adds the Publication Abstract to the page
__TOC__
(as it appears on PubMed at http://www.pubmed.gov), where 7961857 is the PubMed ID number.
</StructureSection>
-->
{{ABSTRACT_PUBMED_7961857}}
 
==About this Structure==
1FIP is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FIP OCA].
 
==Reference==
The structure of Fis mutant Pro61Ala illustrates that the kink within the long alpha-helix is not due to the presence of the proline residue., Yuan HS, Wang SS, Yang WZ, Finkel SE, Johnson RC, J Biol Chem. 1994 Nov 18;269(46):28947-54. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7961857 7961857]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Finkel, S E.]]
[[Category: Finkel SE]]
[[Category: Johnson, R C.]]
[[Category: Johnson RC]]
[[Category: Wang, S S.]]
[[Category: Wang SS]]
[[Category: Yang, W Z.]]
[[Category: Yang W-Z]]
[[Category: Yuan, H S.]]
[[Category: Yuan HS]]
[[Category: Dna-binding protein]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 03:19:46 2008''

Latest revision as of 07:14, 7 February 2024

THE STRUCTURE OF FIS MUTANT PRO61ALA ILLUSTRATES THAT THE KINK WITHIN THE LONG ALPHA-HELIX IS NOT DUE TO THE PRESENCE OF THE PROLINE RESIDUE

1fip, resolution 1.90Å

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