1hlw: Difference between revisions

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{{Seed}}
[[Image:1hlw.png|left|200px]]


<!--
==STRUCTURE OF THE H122A MUTANT OF THE NUCLEOSIDE DIPHOSPHATE KINASE==
The line below this paragraph, containing "STRUCTURE_1hlw", creates the "Structure Box" on the page.
<StructureSection load='1hlw' size='340' side='right'caption='[[1hlw]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1hlw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Dictyostelium_discoideum Dictyostelium discoideum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HLW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HLW FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hlw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hlw OCA], [https://pdbe.org/1hlw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hlw RCSB], [https://www.ebi.ac.uk/pdbsum/1hlw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hlw ProSAT]</span></td></tr>
{{STRUCTURE_1hlw|  PDB=1hlw |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/NDKC_DICDI NDKC_DICDI]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hl/1hlw_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1hlw ConSurf].
<div style="clear:both"></div>


===STRUCTURE OF THE H122A MUTANT OF THE NUCLEOSIDE DIPHOSPHATE KINASE===
==See Also==
 
*[[Nucleoside diphosphate kinase 3D structures|Nucleoside diphosphate kinase 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_11148034}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 11148034 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_11148034}}
 
==About this Structure==
1HLW is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Dictyostelium_discoideum Dictyostelium discoideum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HLW OCA].
 
==Reference==
Chemical rescue of phosphoryl transfer in a cavity mutant: a cautionary tale for site-directed mutagenesis., Admiraal SJ, Meyer P, Schneider B, Deville-Bonne D, Janin J, Herschlag D, Biochemistry. 2001 Jan 16;40(2):403-13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11148034 11148034]
[[Category: Dictyostelium discoideum]]
[[Category: Dictyostelium discoideum]]
[[Category: Nucleoside-diphosphate kinase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Admiraal SJ]]
[[Category: Admiraal, S J.]]
[[Category: Deville-Bonne D]]
[[Category: Deville-Bonne, D.]]
[[Category: Herschlag D]]
[[Category: Herschlag, D.]]
[[Category: Janin J]]
[[Category: Janin, J.]]
[[Category: Meyer P]]
[[Category: Meyer, P.]]
[[Category: Schneider B]]
[[Category: Schneider, B.]]
[[Category: Atp-binding]]
[[Category: Kinase]]
[[Category: Phosphotransferase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 08:22:31 2008''

Latest revision as of 07:28, 7 February 2024

STRUCTURE OF THE H122A MUTANT OF THE NUCLEOSIDE DIPHOSPHATE KINASE

1hlw, resolution 1.90Å

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