2au3: Difference between revisions

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{{Seed}}
[[Image:2au3.png|left|200px]]


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==Crystal Structure of the Aquifex aeolicus primase (Zinc Binding and RNA Polymerase Domains)==
The line below this paragraph, containing "STRUCTURE_2au3", creates the "Structure Box" on the page.
<StructureSection load='2au3' size='340' side='right'caption='[[2au3]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2au3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AU3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AU3 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
{{STRUCTURE_2au3| PDB=2au3 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2au3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2au3 OCA], [https://pdbe.org/2au3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2au3 RCSB], [https://www.ebi.ac.uk/pdbsum/2au3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2au3 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DNAG_AQUAE DNAG_AQUAE] RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.[HAMAP-Rule:MF_00974]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/au/2au3_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2au3 ConSurf].
<div style="clear:both"></div>


===Crystal Structure of the Aquifex aeolicus primase (Zinc Binding and RNA Polymerase Domains)===
==See Also==
 
*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_16285921}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 16285921 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_16285921}}
 
==About this Structure==
2AU3 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AU3 OCA].
 
==Reference==
Crosstalk between primase subunits can act to regulate primer synthesis in trans., Corn JE, Pease PJ, Hura GL, Berger JM, Mol Cell. 2005 Nov 11;20(3):391-401. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16285921 16285921]
[[Category: Aquifex aeolicus]]
[[Category: Aquifex aeolicus]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Berger, J M.]]
[[Category: Berger JM]]
[[Category: Corn, J E.]]
[[Category: Corn JE]]
[[Category: Hura, G L.]]
[[Category: Hura GL]]
[[Category: Pease, P J.]]
[[Category: Pease PJ]]
[[Category: Dna replication]]
[[Category: Rna polymerase]]
[[Category: Toprim]]
[[Category: Zinc ribbon]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 01:38:24 2008''

Latest revision as of 09:14, 14 February 2024

Crystal Structure of the Aquifex aeolicus primase (Zinc Binding and RNA Polymerase Domains)

2au3, resolution 2.00Å

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