2jcp: Difference between revisions

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{{Seed}}
[[Image:2jcp.png|left|200px]]


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==The hyaluronan binding domain of murine CD44==
The line below this paragraph, containing "STRUCTURE_2jcp", creates the "Structure Box" on the page.
<StructureSection load='2jcp' size='340' side='right'caption='[[2jcp]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2jcp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JCP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JCP FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jcp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jcp OCA], [https://pdbe.org/2jcp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jcp RCSB], [https://www.ebi.ac.uk/pdbsum/2jcp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jcp ProSAT]</span></td></tr>
{{STRUCTURE_2jcp| PDB=2jcp |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/CD44_MOUSE CD44_MOUSE] Main cell surface receptor for hyaluronate. Adhesion to mucosal high endothelial venule and to types I and VI collagen. Probably involved in matrix adhesion, lymphocyte activation and lymph node homing.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jc/2jcp_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jcp ConSurf].
<div style="clear:both"></div>


===THE HYALURONAN BINDING DOMAIN OF MURINE CD44===
==See Also==
 
*[[CD44|CD44]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_17293874}}, adds the Publication Abstract to the page
[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 17293874 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_17293874}}
 
==About this Structure==
2JCP is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JCP OCA].
 
==Reference==
Structures of the Cd44-hyaluronan complex provide insight into a fundamental carbohydrate-protein interaction., Banerji S, Wright AJ, Noble M, Mahoney DJ, Campbell ID, Day AJ, Jackson DG, Nat Struct Mol Biol. 2007 Mar;14(3):234-9. Epub 2007 Feb 11. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17293874 17293874]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Single protein]]
[[Category: Banerji S]]
[[Category: Banerji, S.]]
[[Category: Campbell ID]]
[[Category: Campbell, I D.]]
[[Category: Day AJ]]
[[Category: Day, A J.]]
[[Category: Jackson DG]]
[[Category: Jackson, D G.]]
[[Category: Mahoney DJ]]
[[Category: Mahoney, D J.]]
[[Category: Noble MEM]]
[[Category: Noble, M E.M.]]
[[Category: Wright AJ]]
[[Category: Wright, A J.]]
[[Category: Alternative splicing]]
[[Category: Antigen]]
[[Category: Blood group antigen]]
[[Category: C-type lectin]]
[[Category: Cell adhesion]]
[[Category: Extracellular matrix]]
[[Category: Glycoprotein]]
[[Category: Hyauronan]]
[[Category: Lectin]]
[[Category: Link-domain]]
[[Category: Membrane]]
[[Category: Phosphorylation]]
[[Category: Polymorphism]]
[[Category: Proteoglycan]]
[[Category: Pyrrolidone carboxylic acid]]
[[Category: Receptor]]
[[Category: Sugar- binding]]
[[Category: Sugar-binding protein]]
[[Category: Sulfation]]
[[Category: Transmembrane]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 02:58:15 2008''

Latest revision as of 07:46, 7 February 2024

The hyaluronan binding domain of murine CD44

2jcp, resolution 1.30Å

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