1q5m: Difference between revisions

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{{Seed}}
[[Image:1q5m.png|left|200px]]


<!--
==Binary complex of rabbit 20alpha-hydroxysteroid dehydrogenase with NADPH==
The line below this paragraph, containing "STRUCTURE_1q5m", creates the "Structure Box" on the page.
<StructureSection load='1q5m' size='340' side='right'caption='[[1q5m]], [[Resolution|resolution]] 1.32&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1q5m]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q5M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Q5M FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.32&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_1q5m|  PDB=1q5m |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1q5m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1q5m OCA], [https://pdbe.org/1q5m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1q5m RCSB], [https://www.ebi.ac.uk/pdbsum/1q5m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1q5m ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PE2R_RABIT PE2R_RABIT] Can convert prostaglandin E2 to prostaglandin F2-alpha.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/q5/1q5m_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1q5m ConSurf].
<div style="clear:both"></div>


===Binary complex of rabbit 20alpha-hydroxysteroid dehydrogenase with NADPH===
==See Also==
 
*[[Hydroxysteroid dehydrogenase 3D structures|Hydroxysteroid dehydrogenase 3D structures]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_15123423}}, adds the Publication Abstract to the page
[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 15123423 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_15123423}}
 
==About this Structure==
1Q5M is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q5M OCA].
 
==Reference==
Loop relaxation, a mechanism that explains the reduced specificity of rabbit 20alpha-hydroxysteroid dehydrogenase, a member of the aldo-keto reductase superfamily., Couture JF, Legrand P, Cantin L, Labrie F, Luu-The V, Breton R, J Mol Biol. 2004 May 21;339(1):89-102. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15123423 15123423]
[[Category: Oryctolagus cuniculus]]
[[Category: Oryctolagus cuniculus]]
[[Category: Single protein]]
[[Category: Breton R]]
[[Category: Breton, R.]]
[[Category: Cantin L]]
[[Category: Cantin, L.]]
[[Category: Couture JF]]
[[Category: Couture, J F.]]
[[Category: Labrie F]]
[[Category: Labrie, F.]]
[[Category: Legrand P]]
[[Category: Legrand, P.]]
[[Category: Luu-The V]]
[[Category: Luu-The, V.]]
[[Category: Aldo-keto reductase]]
[[Category: Hsd]]
[[Category: Hydroxysteroid dehydrogenase]]
[[Category: Nadph]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 06:45:16 2008''

Latest revision as of 08:13, 14 February 2024

Binary complex of rabbit 20alpha-hydroxysteroid dehydrogenase with NADPH

1q5m, resolution 1.32Å

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