2cg4: Difference between revisions

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{{Seed}}
[[Image:2cg4.png|left|200px]]


<!--
==Structure of E.coli AsnC==
The line below this paragraph, containing "STRUCTURE_2cg4", creates the "Structure Box" on the page.
<StructureSection load='2cg4' size='340' side='right'caption='[[2cg4]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2cg4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CG4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CG4 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ASN:ASPARAGINE'>ASN</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
{{STRUCTURE_2cg4|  PDB=2cg4 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cg4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cg4 OCA], [https://pdbe.org/2cg4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cg4 RCSB], [https://www.ebi.ac.uk/pdbsum/2cg4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cg4 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ASNC_ECOLI ASNC_ECOLI] Activator of asnA transcription; autogenous regulator of its own transcription; and repressor of the expression of gidA at a post-transcriptional level.<ref>PMID:3909107</ref> <ref>PMID:2864330</ref> <ref>PMID:2836709</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cg/2cg4_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cg4 ConSurf].
<div style="clear:both"></div>


===STRUCTURE OF E.COLI ASNC===
==See Also==
 
*[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]]
 
== References ==
<!--
<references/>
The line below this paragraph, {{ABSTRACT_PUBMED_16528101}}, adds the Publication Abstract to the page
__TOC__
(as it appears on PubMed at http://www.pubmed.gov), where 16528101 is the PubMed ID number.
</StructureSection>
-->
{{ABSTRACT_PUBMED_16528101}}
 
==About this Structure==
2CG4 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CG4 OCA].
 
==Reference==
Structural insight into gene transcriptional regulation and effector binding by the Lrp/AsnC family., Thaw P, Sedelnikova SE, Muranova T, Wiese S, Ayora S, Alonso JC, Brinkman AB, Akerboom J, van der Oost J, Rafferty JB, Nucleic Acids Res. 2006 Mar 9;34(5):1439-49. Print 2006. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16528101 16528101]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Akerboom, J.]]
[[Category: Akerboom J]]
[[Category: Alonso, J C.]]
[[Category: Alonso JC]]
[[Category: Ayora, S.]]
[[Category: Ayora S]]
[[Category: Brinkman, A B.]]
[[Category: Brinkman AB]]
[[Category: Muranova, T.]]
[[Category: Muranova T]]
[[Category: Oost, J Van Der.]]
[[Category: Rafferty JB]]
[[Category: Rafferty, J B.]]
[[Category: Sedelnikova SE]]
[[Category: Sedelnikova, S E.]]
[[Category: Thaw P]]
[[Category: Thaw, P.]]
[[Category: Wiese S]]
[[Category: Wiese, S.]]
[[Category: Van der Oost J]]
[[Category: Asnc]]
[[Category: Dna binding]]
[[Category: Dna-binding]]
[[Category: Ffrp]]
[[Category: Lrp family]]
[[Category: Transcription]]
[[Category: Transcription regulation]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 02:35:20 2008''

Latest revision as of 06:38, 1 May 2024

Structure of E.coli AsnC

2cg4, resolution 2.40Å

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