2hqw: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,615 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,615 edits
No edit summary
 
(10 intermediate revisions by the same user not shown)
Line 1: Line 1:
{{Seed}}
[[Image:2hqw.png|left|200px]]


<!--
==Crystal Structure of Ca2+/Calmodulin bound to NMDA Receptor NR1C1 peptide==
The line below this paragraph, containing "STRUCTURE_2hqw", creates the "Structure Box" on the page.
<StructureSection load='2hqw' size='340' side='right'caption='[[2hqw]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2hqw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HQW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HQW FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
{{STRUCTURE_2hqw| PDB=2hqw |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hqw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hqw OCA], [https://pdbe.org/2hqw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hqw RCSB], [https://www.ebi.ac.uk/pdbsum/2hqw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hqw ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CALM1_RAT CALM1_RAT] Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding. Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis. Mediates calcium-dependent inactivation of CACNA1C. Positively regulates calcium-activated potassium channel activity of KCNN2.[UniProtKB:P62158]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hq/2hqw_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hqw ConSurf].
<div style="clear:both"></div>


===Crystal Structure of Ca2+/Calmodulin bound to NMDA Receptor NR1C1 peptide===
==See Also==
 
*[[Calmodulin 3D structures|Calmodulin 3D structures]]
 
__TOC__
<!--
</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_18073110}}, adds the Publication Abstract to the page
[[Category: Homo sapiens]]
(as it appears on PubMed at http://www.pubmed.gov), where 18073110 is the PubMed ID number.
[[Category: Large Structures]]
-->
{{ABSTRACT_PUBMED_18073110}}
 
==About this Structure==
2HQW is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HQW OCA].
 
==Reference==
<ref group="xtra">PMID:18073110</ref><references group="xtra"/>
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Akyol, Z.]]
[[Category: Akyol Z]]
[[Category: Gakhar, L.]]
[[Category: Gakhar L]]
[[Category: Hell, J H.]]
[[Category: Hell JH]]
[[Category: Shea, M A.]]
[[Category: Shea MA]]
[[Category: Sorensen, B R.]]
[[Category: Sorensen BR]]
[[Category: Alternative splicing]]
[[Category: C1 casette]]
[[Category: Calcium channel]]
[[Category: Calmodulin]]
[[Category: Central nervous system]]
[[Category: Ef hand motif]]
[[Category: Er retention signal]]
[[Category: Globular complex]]
[[Category: Glutamate]]
[[Category: Ion channel]]
[[Category: Metal binding protein]]
[[Category: N-methyl-d-aspartate receptor]]
[[Category: Neuronal channel]]
[[Category: Nr1]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 11:52:41 2009''

Latest revision as of 09:34, 14 February 2024

Crystal Structure of Ca2+/Calmodulin bound to NMDA Receptor NR1C1 peptide

2hqw, resolution 1.90Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "https://proteopedia.org/index.php?title=2hqw&oldid=4059101"