Calmodulin 3D structures

3D Structures of Calmodulin

Updated on 29-December-2024

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• Native CaM
  • 1y6w, 1cll, 4bw8, 7t2q - hCaM - human
    
  • 2k61, 2k0e – hCaM – NMR
    
  • 1prw, 1deg – bCaM - bovine
    
  • 4hex – mCaM – mouse
    
  • 1qx5, 3cln – rCaM - rat
    
  • 1up5 – cCaM – chicken
    
  • 1cfc, 1cfd, 1x02, 1dmo – XlCaM - Xenopus laevis - NMR
  • 4cln – DmCaM - Drosophila melanogaster
    
  • 1ooj – CaM – Caenorhabditis elegans
    
  • 1rfj – CaM – potato
    
  • 5a2h – AtCaM-7 – Arabidopsis thaliana
    
  • 1lkj – yCaM – yeast - NMR
  • 2lhh – yCaM + Ca - yeast - NMR
    
  • 1clm, 1osa, 1exr, 5e1p, 5e1n, 5e1k – PtCaM - Paramecium tetraurelia
    
• Mutant CaM
  • 6dah – hCaM (mutant)
    
  • 2k0j, 1sw8, 5ggm, 5tp5, 6gdk, 6gdl, 6y94, 6y95, 8bd2, 8bfg – hCaM (mutant) – NMR
    
  • 1ahr, 2m3s – cCaM (mutant)
    
• CaM N-terminal
  • 2i08, 5dsu - hCaM N-terminal (mutant)
    
  • 1j7o, 1j7p - hCaM N-terminal – NMR
    
  • 3ifk, 3b32 – rCaM N-terminal
    
  • 1f70 - XlCaM N-terminal – NMR
    
  • 2ro8, 2roa - sCaM N-terminal+Ca – NMR - soybean
    
  • 1f54, 1f55 – yCaM N-terminal – NMR
    
• CaM C-terminal
  • 2hf5 - hCaM EF2 EF3 – NMR
    
  • 2lqp - hCaM EF3 EF4 – NMR
    
  • 1cmf, 1cmg – bCaM C-terminal – NMR
    
  • 1fw4 - bCaM C-terminal
    
  • 4rjd – rCaM
    
  • 2kz2, 4bya – cCaM (mutant) - NMR
    
  • 2rrt – XlCaM (mutant) - NMR
    
  • 1f71 - XlCaM C-terminal – NMR
    
  • 2ro9, 2rob - sCaM C-terminal+Ca – NMR
    
  • 2kxw – PtCaM + IQ motif of NAV1.2 – NMR
    
  • 2m5e – PtCaM + Na channel protein
    
• CaM+ cations (non calcium)
  • 2v02 – hCaM+Ba
    
  • 4bw7 – hCaM + Sr
    
  • 3uct – hCaM + Mn + Zn
    
  • 3ucw - hCaM N-terminal + Mg
    
  • 3ucy - hCaM N-terminal + Mg + Zn
    
  • 1ak8 - bCaM N-terminal+Ce – NMR
    
  • 2pq3 – rCaM+Zn
    
  • 2ksz – sCaM N-terminal+Mg – NMR
    
  • 1n0y – PtCaM+Pb
    
• CaM small molecule complexes
  • 1ctr - hCaM+trifluoperazine
    
  • 2kug, 2kuh - hCaM N-terminal EF1 EF2+halothane – NMR
    
  • 6m7h – hCaM + sulfonamide derivative
    
  • 6os4 – hCaM-1 + farnesyl derivative
    
  • 7psz, 7pu9 – hCaM-1 + imidazole derivative
    
  • 9jqi – hCaM-1 + sulfonamide derivative
    
  • 3if7 – bCaM+sphingosylphosphorylcholine
    
  • 1qiv, 1qiw – bCaM+DPDv
    
  • 1a29, 1lin – bCaM+trifluoperazine
    
  • 1xa5 – bCaM+KAR-2
    
  • 2kdu – XlCaM+MUNC13-1 – NMR
    
  • 1mux – XlCaM+W-7 – NMR
    
• CaM complexed with protein CBD domains
  • 5dbr – hCaM + sodium channel peptide
    
  • 4gow, 4umo, 4v0c – hCaM + potassium channel peptide
    
  • 3hr4, 2ll6, 2ll7, 5tp6 - hCaM+nitric oxide synthase CBD
    
  • 1yr5, 1wrz, 2y4v – hCaM+death-associated protein kinase 1 (DAP)
    
  • 2l7l - hCaM+ CaM-dependent protein kinase 1 CBD
    
  • 6hcs - hCaM+ CaM-dependent protein kinase 2 peptide
    
  • 7zrq – hCaM (mutant) + CaM-dependent protein kinase 2 peptide
    
  • 2m0j, 2m0k - hCaM+olfactory channel peptide
    
  • 2kne – hCaM+PMCA C-terminal CBD
    
  • 4upu - hCaM+ IP3 3-K CBD
    
  • 6y4p – hCaM-1+ ryanodine receptor CBD
    
  • 6jv2 – hCaM-1+ ryanodine receptor CBD – Cryo EM
    
  • 6ji8, 6jiu, 6jrs, 6x32, 6x33, 6x35, 6x36 – hCaM-1+ ryanodine receptor CBD + FKBP1B – Cryo EM
    
  • 6xxf, 6y4o, 7kl5 – hCaM-2+ ryanodine receptor CBD
    
  • 8k9z, 8ka0, 8ka1, 8ka2 – hCaM-2+ RID-dependent transforming NADase CBD
    
  • 3ewt, 3ewv – hCaM+TNFR fragment
    
  • 2w73, 2jzi, 2r28 – hCaM+Ser/Thr phosphatase CBD
    
  • 3bya – hCaM+glutamate receptor peptide
    
  • 3g43, 2vay, 2f3y, 2f3z, 2be6, 2lqc, 3oxq – hCaM+calcium channel CAV1.2
    
  • 7l8v - hCaM+calcium channel CAV1.2 peptide – NMR
    
  • 3dve, 3dvj, 3dvk, 3dvm - hCaM+calcium channel CAV2.2
    
  • 5jth, 5jqa – hCaM + myosin light chain kinase peptide
    
  • 2k0f, 2lv6 – hCaM+myosin light chain kinase peptide – NMR
    
  • 1zuz – hCaM+DRP kinase peptide
    
  • 1l7z – hCaM+CAP-23/NAP-22 CBD
    
  • 1cdl - hCaM+CaM dependent kinase CBD
    
  • 1iwq - hCaM+MARCKS CBD
    
  • 3sui – hCaM + capsaicin receptor peptide
    
  • 2m55 – hCaM + α-synuclein peptide
    
  • 5nin – hCaM + A-kinase anchor peptide
    
  • 7bf1, 7bf2 – hCaM + A-kinase anchor peptide
    
  • 7shq – hCaM-1 + creatine kinase peptide - NMR
    
  • 5j8h - hCaM + elongation factor 2 kinase CBD – NMR
    
  • 5dow - hCaM + chloride anion exchanger CBD
    
  • 6zbi – hCaM-1 + sodium/hydrogen anion exchanger CBD - NMR
    
  • 6sz5 – hCaM-2 + NADPH oxidase peptide
    
  • 2lgf – hCaM + selectin peptide
    
  • 2fot - bCaM+α-II spectrin CBD
    
  • 2f2o, 2f2p – bCaM+calcium
    
  • 1xa5 – bCaM+KAR-2
    
  • 1cm1, 1cm4, 1cdm - bCaM+CaM dependent kinase CBD
    
  • 4e50 – mCam/linker/neurogranin IQ motif
    
  • 4e53 – mCam/linker/neuromoduin IQ motif
    
  • 1niw - rCaM+nitric oxide synthase CBD
    
  • 2hqw - rCaM+glutamate receptor peptide
    
  • 3bxk, 3bxl, 4ehq, 4j9y, 4j9z – rCaM+ calcium channel peptide
    
  • 1g4y, 3sjq, 4g27, 4g28, 4qnh - rCaM+ potassium channel CBD
    
  • 2ygg – rCaM + Na/H exchanger CBD
    
  • 7nqc – rCaM + peptide - NMR
    
  • 2mgu – rCaM + HIV-1 matrix protein CBD – NMR
    
  • 1qx7 – rCaM+potassium channel peptide
    
  • 5hit – cCaM + potassium channel peptide
    
  • 3gp2 – cCaM+CaM kinase II δ chain
    
  • 2dfs – cCaM+myosin 5A
    
  • 2o5g – cCaM+ myosin light chain kinase peptide
    
  • 2bcx – cCaM+ryanodine receptor 1 peptide
    
  • 3gof, 2o60 – cCaM+nitric oxide synthase CBD
    
  • 1cff - XlCaM+ calcium channel CBD - NMR
    
  • 1sy9 – XlCaM+olfactory channel peptide
    
  • 1nwd – XlCaM+glutamate decarboxylase CBD
    
  • 1iq5 – XlCaM+CaM dependent kinase CBD
    
  • 1ckk - XlCaM+CaM dependent kinase CBD - NMR
    
  • 2llo, 2llq – XlCaM EF-hand domain + estrogen receptor CBD – NMR
    
  • 5t0x - XlCaM + estrogen receptor CBD – NMR
    
  • 2mes, 5j7j – XlCaM +PSD95 peptide - NMR
    
  • 2mg5 - XlCaM+nitric oxide synthase peptide - NMR
    
  • 2bbm, 2bbn - DmCaM+myosin light chain kinase peptide
    
  • 1mxe – DmCaM+rCaMKI CBD
    
  • 5k8q – faCaM + STRA6 peptide – fall armyworm
    
  • 2kn2 – sCaM C-terminal+NtMKP1 CBD – NMR
    
  • 2l1w – sCaM + vacuolar calcium ATPase peptide – NMR
    
  • 4aqr – AtCaM-7 + calcium-transporting ATPase peptide
    
• Calmodulin complex with myosin
  • 4l79, 4byf, 5v7x – hCaM + myosin 1B
    
  • 6c1h, 6c1g – hCaM + myosin 1B + actin
    
  • 6c1d – hCaM + myosin 1B + actin + phalloidin
    
  • 5wsv, 5wsu – hCaM + myosin VII-A
    
  • 5i0i – hCaM + myosin X
    
  • 2bki, 2bkh – pCaM + myosin VI – pig
    
  • 4zlk – mCaM + myosin VA
    
  • 8of8 – mCaM + actin + myosin VA – Cryo EM
    
  • 2ix7 – mCaM + myosin-5A
    
  • 7yv9 – mCaM + myosin VI – Cryo EM
    
  • 4r8g – rCaM + myosin 1B
    
  • 3ek4, 3ek7, 3ek8, 3ekh, 3ekj, 3evr, 3evu, 3evv, 3o77, 3o78 – rCaM/DFP/myosin light chain kinase
    
  • 2dfs – cCaM + myosin 5A
    
  • 6bnv – cCaM + myosin 6 + actin - Cryo EM
    
  • 2vas, 2vb6, 3gn4, 3l9i, 4dbp, 4dbq, 2x51, 4anj – DmCaM + pMyosin IV
    
  • 4pjj - DmCaM + pMyosin VI
    
  • 6ui4 - CaM + Myosin I + fungicide – Fusarium graminearum
    
• Calmodulin complex with ion channels
  • 4djc, 2l53, 4ovn - hCaM + sodium channel protein type V α subunit
    
  • 4dck, 4jpz - hCaM + sodium channel protein type V α subunit + fibroblast growth factor 13
    
  • 4jq0 - hCaM + sodium channel protein type V α subunit + fibroblast growth factor 12
    
  • 5k7l, 6pbx, 6pby, 8eow, 8ep0, 8ep1 - hCaM + potassium channel EAG1 – Cryo EM
    
  • 5j03, 6feh, 6feg, 6b8q, 6b8p, 6b8n, 6b8m, 6b8l, 5vms - hCaM + potassium channel subfamily KQT
    
  • 6uzz, 7tcp, 7xni, 8sik, 8sim, 8sin – hCaM-1+ potassium channel subfamily KQT – Cryo EM
    
  • 7xnl, 7xnn, 8ijk, 8j01, 8j02, 8j03, 8j04, 8j05, 8w4u, 8x43 – hCaM-1+ potassium channel subfamily KQT + ligand – Cryo EM
    
  • 8j00 – hCaM-1+ potassium channel subfamily KQT + cannabidiol – Cryo EM
    
  • 7xnk – hCaM-1+ potassium channel subfamily KQT + enhancer – Cryo EM
    
  • 9cui, 9cuk – hCaM-1+ calcium channel TRPV6 – Cryo EM
    
  • 8bx7, 8dgh, 8dgk – hCaM-1+ CNG channel peptide – NMR
    
  • 7byl – hCaM-3 + potassium channel subfamily KQT – Cryo EM
    
  • 7bym, 7byn, 7vnr – hCaM-3 + potassium channel subfamily KQT + drug – Cryo EM
    
  • 7vnp, 7vnq – hCaM-3 + potassium channel subfamily KQT + PTDINS – Cryo EM
    
  • 6v00, 6v01 – hCaM-1 + potassium channel subfamily KQT + KCNE3 – Cryo EM
    
  • 7tci – hCaM-1 + potassium channel subfamily KQT + piperidine derivative – Cryo EM
    
  • 7cr3 – hCaM-3 + potassium channel subfamily KQT – Cryo EM
    
  • 7cr4, 7cr7 – hCaM-3 + potassium channel subfamily KQT + drug – Cryo EM
    
  • 5wc5, 5wbx, 5v03, 5v02, 6czq – hCaM + potassium channel KCAT2.2
    
  • 6cnm, 6cnn, 6cno – hCaM + potassium channel Sk4
    
  • 6ale – hCaM-2 + potassium channel Sk2
    
  • 7vuo, 7vvd, 7vvh – hCaM-1 (mutant) + potassium channel Kv7.1 C terminal
    
  • 6n5w – hCaM-1 + potassium channel Kv7.4
    
  • 6e2f, 6e2g, 6dmw – hCaM + transient receptor potential cation channel – Cryo EM
    
  • 5oeo – hCaM + transient receptor potential cation channel – NMR
    
  • 6ctb - hCaM + calcium channel Cav1.2 - NMR
    
  • 6but – hCaM-1 + IQ motif of NaV1.2
    
  • 6u3a – hCaM-1 (mutant) + IQ motif of NaV1.2
    
  • 6mue – hCaM-1 + IQ motif of NaV1.4
    
  • 6mud – hCaM-1 + IQ motif of NaV1.5
    
  • 6dad, 6dae, 6daf, 6u39, 6u3b, 6u3d - hCaM (mutant) + calcium channel Cav1.2
    
  • 6o20 – bCaM + calcium channel TRPV5 – Cryo EM
    
  • 6mba, 6mc9 - rCaM + sodium channel protein type IV α subunit
    
• Calmodulin complex with other proteins
  • 3j41 – hCaM + lens fiber major intrinsic protein – Cryo EM
    
  • 4lzx, 4m1l - hCaM + IQ domain-containing protein G
    
  • 4q57 – hCaM N-terminal + plectin
    
  • 4q5u – hCaM + calcineurin
    
  • 2x0g – hCaM + death-associated protein kinase 1
    
  • 6paw – hCaM-1 + death-associated protein kinase 2
    
  • 6k4k, 6k4l – hCaM-1 + SidJ
    
  • 7ppo, 7pqe – hCaM-1 + SidJ + SdeA – Cryo EM
    
  • 6k4r – hCaM-1 + SidJ + AMP
    
  • 7sx3, 7sx4, 7wji – hCaM-1 in channelosome – Cryo EM
    
  • 7xn4 – hCaM-1 + caspase-3 + CopC + NAD – Cryo EM
    
  • 7xn5, 7xn6 – hCaM-1 + caspase-3 + CopC + ADPR – Cryo EM
    
  • 7wzs – hCaM-1 + caspase-7 + CopC
    
  • 7wr4, 7wr5 – hCaM-1 + caspase-4 + OspC3 + NAD – Cryo EM
    
  • 7wr3 – hCaM-1 + OspC3
    
  • 8jfk, 8xya, 8xyb – hCaM-1 + phosphorylase B kinase + farnesyl – Cryo EM
    
  • 8fo6 – hCaM-1 + EEF-2 kinase
    
  • 8gn4 – hCaM-1 + EEF-2 kinase – Cryo EM
    
  • 8fny – hCaM-1 + EEF-2 kinase + ADP + ATP
    
  • 8gm5 – hCaM-1 + EEF-2 kinase + ADP + inhibitor
    
  • 7vmb – hCaM-1 + IQSEC1
    
  • 6oqq – hCaM-2 + SidJ – Cryo EM
    
  • 6plm – hCaM-2 + SidJ + AMP
    
  • 7mir, 7mis – hCaM-2 + SidJ + SdeA + AMP + ATP – Cryo EM
    
  • 6pjx – hCaM + GRK5
    
  • 7b1g – hCaM + TRPC4
    
  • 7cqp – hCaM + TRPC4 peptide
    
  • 7wzs – hCaM + caspase + CopC
    
  • 6yns, 6ynu – hCaM + P458
    
  • 8ahs – hCaM + melittin
    
  • 6o20 – bCaM + TRPV5 – Cryo EM
    
  • 2k3s – XlCaM + smoothelin-like protein 1 – NMR
    
  • 5sy1 – faCaM + STRA6
    
  • 6xwv – DmCaM + ryanodine receptor
    
  • 6s5t – yCaM + SidJ
    
  • 1qs7, 1qtx – EcCaM + RS20 – Escherichia coli
    
  • 1vrk – EcCaM (mutant) + RS20
    
  • 4ds7 – CaM + spindle pole body component 10 – Kluyveromyces lactis
    
  • 2col, 1yrt, 1yru – BpCaM +a denyl cyclase – Bordetella pertussis
    
  • 1zot – BpCaM C-terminal+ adenyl cyclase
    
  • 1xfu, 1xfv, 1xfw, 1xfx, 1xfy, 1xfz, 1y0v, 1sk6, 1pk0, 1lvc, 1k90, 1k93 - CaM + adenyl cyclase – Bacillus anthracis
    
  • 7jts – CrCaM + Dynein + FAP207 + FAP253 + radial spoke protein 3 – Chlamydomonas renhardtii – Cryo EM
    
  • 8bwy – CrCaM in dynein arm complex – Cryo EM
    
  • 8aht – CaM + melittin – Plasmodium falciparum
    
  • 8th8 – CaM-7-2 in nexin-dynein complex – Tetrahymena thermophila – Cryo EM
    

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel