1yn7: Difference between revisions

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New page: left|200px<br /><applet load="1yn7" size="450" color="white" frame="true" align="right" spinBox="true" caption="1yn7, resolution 2.2Å" /> '''Crystal structure of ...
 
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[[Image:1yn7.gif|left|200px]]<br /><applet load="1yn7" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1yn7, resolution 2.2&Aring;" />
'''Crystal structure of a mouse MHC class I protein, H2-Db, in complex with a mutated peptide (R7A) of the influenza A acid polymerase'''<br />


==About this Structure==
==Crystal structure of a mouse MHC class I protein, H2-Db, in complex with a mutated peptide (R7A) of the influenza A acid polymerase==
1YN7 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Active as [http://en.wikipedia.org/wiki/RNA-directed_RNA_polymerase RNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.48 2.7.7.48] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1YN7 OCA].  
<StructureSection load='1yn7' size='340' side='right'caption='[[1yn7]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1yn7]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Influenza_A_virus_(A/swine/Iowa/15/1930(H1N1)) Influenza A virus (A/swine/Iowa/15/1930(H1N1))] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YN7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YN7 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yn7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yn7 OCA], [https://pdbe.org/1yn7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yn7 RCSB], [https://www.ebi.ac.uk/pdbsum/1yn7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yn7 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HA11_MOUSE HA11_MOUSE] Involved in the presentation of foreign antigens to the immune system.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yn/1yn7_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1yn7 ConSurf].
<div style="clear:both"></div>


==Reference==
==See Also==
Favorite flavors of surfaces., Jones EY, Nat Immunol. 2005 Apr;6(4):365-6. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15785764 15785764]
*[[Beta-2 microglobulin 3D structures|Beta-2 microglobulin 3D structures]]
*[[MHC 3D structures|MHC 3D structures]]
*[[MHC I 3D structures|MHC I 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Protein complex]]
[[Category: Doherty PC]]
[[Category: RNA-directed RNA polymerase]]
[[Category: Dunstone MA]]
[[Category: Doherty, P.C.]]
[[Category: Kedzierska K]]
[[Category: Dunstone, M.A.]]
[[Category: Komodromou H]]
[[Category: Gruta, N.L.La.]]
[[Category: La Gruta NL]]
[[Category: Kedzierska, K.]]
[[Category: McCluskey J]]
[[Category: Komodromou, H.]]
[[Category: Purcell AW]]
[[Category: McCluskey, J.]]
[[Category: Rossjohn J]]
[[Category: Purcell, A.W.]]
[[Category: Turner SJ]]
[[Category: Rossjohn, J.]]
[[Category: Walden H]]
[[Category: Turner, S.J.]]
[[Category: Webb AI]]
[[Category: Walden, H.]]
[[Category: Webby R]]
[[Category: Webb, A.I.]]
[[Category: Xie W]]
[[Category: Webby, R.]]
[[Category: Xie, W.]]
[[Category: h2-db]]
[[Category: influenza a]]
[[Category: mhc class 1]]
[[Category: peptide of acid polymerase]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 06:55:32 2007''

Latest revision as of 07:42, 30 October 2024

Crystal structure of a mouse MHC class I protein, H2-Db, in complex with a mutated peptide (R7A) of the influenza A acid polymerase

1yn7, resolution 2.20Å

Drag the structure with the mouse to rotate

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