1cnz: Difference between revisions

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{{Seed}}
[[Image:1cnz.png|left|200px]]


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==3-ISOPROPYLMALATE DEHYDROGENASE (IPMDH) FROM SALMONELLA TYPHIMURIUM==
The line below this paragraph, containing "STRUCTURE_1cnz", creates the "Structure Box" on the page.
<StructureSection load='1cnz' size='340' side='right'caption='[[1cnz]], [[Resolution|resolution]] 1.76&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1cnz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CNZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CNZ FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.76&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_1cnz| PDB=1cnz |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1cnz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cnz OCA], [https://pdbe.org/1cnz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1cnz RCSB], [https://www.ebi.ac.uk/pdbsum/1cnz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1cnz ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/LEU3_SALTY LEU3_SALTY] Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.[HAMAP-Rule:MF_01033]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cn/1cnz_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1cnz ConSurf].
<div style="clear:both"></div>


===3-ISOPROPYLMALATE DEHYDROGENASE (IPMDH) FROM SALMONELLA TYPHIMURIUM===
==See Also==
 
*[[Isopropylmalate dehydrogenase|Isopropylmalate dehydrogenase]]
 
__TOC__
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</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_9086278}}, adds the Publication Abstract to the page
[[Category: Large Structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 9086278 is the PubMed ID number.
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
-->
[[Category: Kryger G]]
{{ABSTRACT_PUBMED_9086278}}
[[Category: Lovett ST]]
 
[[Category: Oshima T]]
==About this Structure==
[[Category: Petsko GA]]
1CNZ is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Salmonella_typhimurium Salmonella typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CNZ OCA].
[[Category: Ringe D]]
 
[[Category: Wallon G]]
==Reference==
<ref group="xtra">PMID:9086278</ref><references group="xtra"/>
[[Category: Salmonella typhimurium]]
[[Category: Kryger, G.]]
[[Category: Lovett, S T.]]
[[Category: Oshima, T.]]
[[Category: Petsko, G A.]]
[[Category: Ringe, D.]]
[[Category: Wallon, G.]]
[[Category: Dehydrogenase]]
[[Category: Leucine biosynthetic pathway]]
[[Category: Nad-dependant enzyme]]
[[Category: Oxidoreductase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 18:41:21 2009''

Latest revision as of 05:57, 3 April 2024

3-ISOPROPYLMALATE DEHYDROGENASE (IPMDH) FROM SALMONELLA TYPHIMURIUM

1cnz, resolution 1.76Å

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