1msw: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
 
(11 intermediate revisions by the same user not shown)
Line 1: Line 1:
{{Seed}}
[[Image:1msw.png|left|200px]]


<!--
==Structural basis for the transition from initiation to elongation transcription in T7 RNA polymerase==
The line below this paragraph, containing "STRUCTURE_1msw", creates the "Structure Box" on the page.
<StructureSection load='1msw' size='340' side='right'caption='[[1msw]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1msw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_T7 Escherichia phage T7]. The April 2003 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''RNA Polymerase''  by David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2003_4 10.2210/rcsb_pdb/mom_2003_4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MSW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MSW FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1msw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1msw OCA], [https://pdbe.org/1msw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1msw RCSB], [https://www.ebi.ac.uk/pdbsum/1msw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1msw ProSAT]</span></td></tr>
{{STRUCTURE_1msw| PDB=1msw |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/RPOL_BPT7 RPOL_BPT7] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Responsible for the transcription of the late genes of T7. It is rifampicin-resistant. It recognizes a specific promoter sequence, unwinds the double-stranded RNA to expose the coding strand for templating, initiates transcription preferentially with a purine.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ms/1msw_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1msw ConSurf].
<div style="clear:both"></div>


===Structural basis for the transition from initiation to elongation transcription in T7 RNA polymerase===
==See Also==
 
*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
 
__TOC__
<!--
</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_12242451}}, adds the Publication Abstract to the page
[[Category: Escherichia phage T7]]
(as it appears on PubMed at http://www.pubmed.gov), where 12242451 is the PubMed ID number.
[[Category: Large Structures]]
-->
[[Category: RCSB PDB Molecule of the Month]]
{{ABSTRACT_PUBMED_12242451}}
 
==About this Structure==
1MSW is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t7 Enterobacteria phage t7]. The April 2003 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''RNA Polymerase''  by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2003_4 10.2210/rcsb_pdb/mom_2003_4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MSW OCA].
 
==Reference==
<ref group="xtra">PMID:12242451</ref><references group="xtra"/>
[[Category: DNA-directed RNA polymerase]]
[[Category: Enterobacteria phage t7]]
[[Category: RNA Polymerase]]
[[Category: RNA Polymerase]]
[[Category: Steitz, T A.]]
[[Category: Steitz TA]]
[[Category: Yin, Y W.]]
[[Category: Yin YW]]
[[Category: T7rnap elongation complex]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 23:56:12 2009''

Latest revision as of 07:48, 14 February 2024

Structural basis for the transition from initiation to elongation transcription in T7 RNA polymerase

1msw, resolution 2.10Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA