3hob: Difference between revisions
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[[Image:3hob.png|left|200px]] | [[Image:3hob.png|left|200px]] | ||
{{STRUCTURE_3hob| PDB=3hob | SCENE= }} | {{STRUCTURE_3hob| PDB=3hob | SCENE= }} | ||
===Factor VIII Trp2313-His2315 segment is involved in membrane binding as shown by crystal structure of complex between factor VIII C2 domain and an inhibitor=== | ===Factor VIII Trp2313-His2315 segment is involved in membrane binding as shown by crystal structure of complex between factor VIII C2 domain and an inhibitor=== | ||
{{ABSTRACT_PUBMED_20089867}} | {{ABSTRACT_PUBMED_20089867}} | ||
==About this Structure== | ==About this Structure== | ||
[[3hob]] is a 2 chain structure of [[Factor VIII]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HOB OCA]. | |||
==See Also== | |||
*[[Factor VIII|Factor VIII]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID: | <ref group="xtra">PMID:020089867</ref><references group="xtra"/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Liu, Z.]] | [[Category: Liu, Z.]] | ||
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[[Category: Blood clotting]] | [[Category: Blood clotting]] | ||
[[Category: Blood coagulation]] | [[Category: Blood coagulation]] | ||
[[Category: Disease mutation]] | [[Category: Disease mutation]] | ||
[[Category: Disulfide bond]] | [[Category: Disulfide bond]] | ||
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[[Category: Hemophilia]] | [[Category: Hemophilia]] | ||
[[Category: Metal-binding]] | [[Category: Metal-binding]] | ||
[[Category: Secreted]] | [[Category: Secreted]] | ||
[[Category: Sulfation]] | [[Category: Sulfation]] | ||
Revision as of 00:56, 27 July 2012
Factor VIII Trp2313-His2315 segment is involved in membrane binding as shown by crystal structure of complex between factor VIII C2 domain and an inhibitor
Template:ABSTRACT PUBMED 20089867
About this Structure
3hob is a 2 chain structure of Factor VIII with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Liu Z, Lin L, Yuan C, Nicolaes GA, Chen L, Meehan EJ, Furie B, Furie B, Huang M. Trp2313-His2315 of factor VIII C2 domain is involved in membrane binding: structure of a complex between the C2 domain and an inhibitor of membrane binding. J Biol Chem. 2010 Mar 19;285(12):8824-9. Epub 2010 Jan 20. PMID:20089867 doi:10.1074/jbc.M109.080168
