1ab4: Difference between revisions

Revision as of 23:00, 26 December 2010

Activity:

DNA topoisomerase (ATP-hydrolyzing), with EC number 5.99.1.3

Structural annotation:
Resources:	CATH : 1Ab4001, 1Ab4002, 1Ab4003 InterPro : Ipr002205, Ipr005743, Ipr013758, Ipr013757, Ipr013760, Ipr006691 Pfam : PF00521 SCOP : d1ab4__ UniProt : P0AES4

Functional annotation:
Cellular component:	membrane fraction cytoplasm chromosome
Biological process:	response to antibiotic DNA metabolic process DNA topological change DNA unwinding during replication
Molecular function:	DNA binding DNA topoisomerase activity ATP binding isomerase activity DNA topoisomerase (ATP-hydrolyzing) activity

Evolutionary conservation:

Toggle Conservation Colors:	Rows = identical sequences:
Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, PDBsum, RCSB

Coordinates:

save as pdb, mmCIF, xml

1ab4 is a 1 chain structure of Gyrase with sequence from Escherichia coli. Full crystallographic information is available from OCA.

Morais Cabral JH, Jackson AP, Smith CV, Shikotra N, Maxwell A, Liddington RC. Crystal structure of the breakage-reunion domain of DNA gyrase. Nature. 1997 Aug 28;388(6645):903-6. PMID:9278055 doi:10.1038/42294

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