Telomerase 3D structures: Difference between revisions
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[[Image:Tert.png|left|200px|thumb|Structure of the catalytic subunit of telomerase, TERT, [[3du5]]]] | [[Image:Tert.png|left|200px|thumb|Structure of the catalytic subunit of telomerase, TERT, [[3du5]]]] | ||
{{ | {{STRUCTURE_2r4g| PDB=2r4g | SIZE=400| SCENE= |right|CAPTION=RNA-binding domain of telomerase complex with Br- ions, [[2r4g]] }} | ||
[[Telomerase]] (TEL) adds DNA repeats to the tail end of telomeres. It carries its own RNA. The human TEL is composed of 2 [[Telomerase Reverse Transcriptase]] (TERT), 2 Telomerase RNA (TERC) and 2 dyskerin (DKC1) molecules. The images at the left and at the right correspond to one representative Telomerase structure, ''i.e.'' crystal structure of catalytic subunit of telomerase, TERT, from ''Tribolium castaneum'' ([[3du5]]). | [[Telomerase]] (TEL) adds DNA repeats to the tail end of telomeres. It carries its own RNA. The human TEL is composed of 2 [[Telomerase Reverse Transcriptase]] (TERT), 2 Telomerase RNA (TERC) and 2 dyskerin (DKC1) molecules. The images at the left and at the right correspond to one representative Telomerase structure, ''i.e.'' crystal structure of catalytic subunit of telomerase, TERT, from ''Tribolium castaneum'' ([[3du5]]). | ||
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[[3kyl]], [[3du5]], [[3du6]] – TERT+DNA – ''Tribolium castaneum''<br /> | [[3kyl]], [[3du5]], [[3du6]] – TERT+DNA – ''Tribolium castaneum''<br /> | ||
[[2r4g]] – TtTERT RNA binding domain | [[2r4g]] – TtTERT RNA binding domain – ''Tetrahymena thermophila''<br /> | ||
[[2b2a]] – TtTERT (mutant)<br /> | [[2b2a]] – TtTERT (mutant)<br /> | ||
[[2fey]] - TtTERC RNA P2b hairpin – NMR<br /> | [[2fey]] - TtTERC RNA P2b hairpin – NMR<br /> | ||
