1w72: Difference between revisions

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==About this Structure==
==About this Structure==
[[1w72]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W72 OCA].  
[[1w72]] is a 10 chain structure of [[Beta-2 microglobulin]] and [[Major histocompatibility complex]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W72 OCA].  
 
==See Also==
*[[Beta-2 microglobulin]]
*[[Major histocompatibility complex]]


==Reference==
==Reference==
<ref group="xtra">PMID:15537658</ref><ref group="xtra">PMID:10884427</ref><ref group="xtra">PMID:12097420</ref><references group="xtra"/>
<ref group="xtra">PMID:015537658</ref><ref group="xtra">PMID:010884427</ref><ref group="xtra">PMID:012097420</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Alings, C.]]
[[Category: Alings, C.]]
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[[Category: Wille, G.]]
[[Category: Wille, G.]]
[[Category: Ziegler, A.]]
[[Category: Ziegler, A.]]
[[Category: Complex]]
[[Category: Hla]]
[[Category: Hla/fab fragment]]
[[Category: Hla/fab fragment]]
[[Category: Human leucocyte antigen]]
[[Category: Human leucocyte antigen]]
[[Category: Immune system]]
[[Category: Immune system]]
[[Category: Mage]]
[[Category: Mhc-i]]
[[Category: Mhc-i]]
[[Category: Peptide-specific fab]]
[[Category: Peptide-specific fab]]
[[Category: Tcr-like binding]]
[[Category: Tcr-like binding]]

Revision as of 06:01, 24 August 2011

File:1w72.png

Template:STRUCTURE 1w72

CRYSTAL STRUCTURE OF HLA-A1:MAGE-A1 IN COMPLEX WITH FAB-HYB3

Template:ABSTRACT PUBMED 15537658

About this Structure

1w72 is a 10 chain structure of Beta-2 microglobulin and Major histocompatibility complex with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Hulsmeyer M, Chames P, Hillig RC, Stanfield RL, Held G, Coulie PG, Alings C, Wille G, Saenger W, Uchanska-Ziegler B, Hoogenboom HR, Ziegler A. A major histocompatibility complex-peptide-restricted antibody and t cell receptor molecules recognize their target by distinct binding modes: crystal structure of human leukocyte antigen (HLA)-A1-MAGE-A1 in complex with FAB-HYB3. J Biol Chem. 2005 Jan 28;280(4):2972-80. Epub 2004 Nov 10. PMID:15537658 doi:10.1074/jbc.M411323200
  2. Chames P, Hufton SE, Coulie PG, Uchanska-Ziegler B, Hoogenboom HR. Direct selection of a human antibody fragment directed against the tumor T-cell epitope HLA-A1-MAGE-A1 from a nonimmunized phage-Fab library. Proc Natl Acad Sci U S A. 2000 Jul 5;97(14):7969-74. PMID:10884427
  3. Chames P, Willemsen RA, Rojas G, Dieckmann D, Rem L, Schuler G, Bolhuis RL, Hoogenboom HR. TCR-like human antibodies expressed on human CTLs mediate antibody affinity-dependent cytolytic activity. J Immunol. 2002 Jul 15;169(2):1110-8. PMID:12097420 doi:10.4049/jimmunol.169.2.1110

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