3ara: Difference between revisions
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===Discovery of Novel Uracil Derivatives as Potent Human dUTPase Inhibitors=== | ===Discovery of Novel Uracil Derivatives as Potent Human dUTPase Inhibitors=== | ||
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==About this Structure== | ==About this Structure== | ||
[[3ara]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ARA OCA]. | [[3ara]] is a 3 chain structure of [[Deoxyuridine 5'-triphosphate nucleotidohydrolase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ARA OCA]. | ||
==See Also== | |||
*[[Deoxyuridine 5'-triphosphate nucleotidohydrolase|Deoxyuridine 5'-triphosphate nucleotidohydrolase]] | |||
==Reference== | |||
<ref group="xtra">PMID:022404301</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: DUTP diphosphatase]] | [[Category: DUTP diphosphatase]] | ||
Revision as of 05:00, 30 May 2012
Discovery of Novel Uracil Derivatives as Potent Human dUTPase Inhibitors
Template:ABSTRACT PUBMED 22404301
About this Structure
3ara is a 3 chain structure of Deoxyuridine 5'-triphosphate nucleotidohydrolase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Miyakoshi H, Miyahara S, Yokogawa T, Chong KT, Taguchi J, Endoh K, Yano W, Wakasa T, Ueno H, Takao Y, Nomura M, Shuto S, Nagasawa H, Fukuoka M. Synthesis and discovery of N-carbonylpyrrolidine- or N-sulfonylpyrrolidine-containing uracil derivatives as potent human deoxyuridine triphosphatase inhibitors. J Med Chem. 2012 Apr 12;55(7):2960-9. Epub 2012 Mar 26. PMID:22404301 doi:10.1021/jm201627n
