3pe2: Difference between revisions
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[[Image:3pe2.png|left|200px]] | [[Image:3pe2.png|left|200px]] | ||
{{STRUCTURE_3pe2| PDB=3pe2 | SCENE= }} | {{STRUCTURE_3pe2| PDB=3pe2 | SCENE= }} | ||
===Crystal structure of human protein kinase CK2 in complex with the inhibitor CX-5011=== | ===Crystal structure of human protein kinase CK2 in complex with the inhibitor CX-5011=== | ||
{{ABSTRACT_PUBMED_21870818}} | {{ABSTRACT_PUBMED_21870818}} | ||
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==See Also== | ==See Also== | ||
*[[Casein kinase]] | *[[Casein kinase|Casein kinase]] | ||
==Reference== | ==Reference== | ||
Revision as of 01:45, 27 July 2012
Crystal structure of human protein kinase CK2 in complex with the inhibitor CX-5011
Template:ABSTRACT PUBMED 21870818
About this Structure
3pe2 is a 1 chain structure of Casein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Battistutta R, Cozza G, Pierre F, Papinutto E, Lolli G, Sarno S, O'Brien SE, Siddiqui-Jain A, Haddach M, Anderes K, Ryckman DM, Meggio F, Pinna LA. Unprecedented selectivity and structural determinants of a new class of protein kinase CK2 inhibitors in clinical stage for the treatment of cancer. Biochemistry. 2011 Aug 26. PMID:21870818 doi:10.1021/bi2008382
- Cozza G, Mazzorana M, Papinutto E, Bain J, Elliott M, di Maira G, Gianoncelli A, Pagano MA, Sarno S, Ruzzene M, Battistutta R, Meggio F, Moro S, Zagotto G, Pinna LA. Quinalizarin as a potent, selective and cell-permeable inhibitor of protein kinase CK2. Biochem J. 2009 Jul 15;421(3):387-95. PMID:19432557 doi:10.1042/BJ20090069
