2e6f: Difference between revisions
From Proteopedia
Jump to navigationJump to search
m Protected "2e6f" [edit=sysop:move=sysop] |
No edit summary |
||
| Line 1: | Line 1: | ||
{{STRUCTURE_2e6f| PDB=2e6f | SCENE= }} | {{STRUCTURE_2e6f| PDB=2e6f | SCENE= }} | ||
===Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with oxonate=== | ===Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with oxonate=== | ||
==Function== | |||
[[http://www.uniprot.org/uniprot/PYRD_TRYCC PYRD_TRYCC]] Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor. Molecular oxygen can replace fumarate in vitro. | |||
==About this Structure== | |||
[[2e6f]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trycr Trycr]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E6F OCA]. | |||
- | |||
== | ==See Also== | ||
[[ | *[[Dihydroorotate dehydrogenase|Dihydroorotate dehydrogenase]] | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:018808149</ref><references group="xtra"/> | <ref group="xtra">PMID:018808149</ref><references group="xtra"/><references/> | ||
[[Category: | [[Category: Trycr]] | ||
[[Category: Aoki, T.]] | [[Category: Aoki, T.]] | ||
[[Category: Harada, S.]] | [[Category: Harada, S.]] | ||
Revision as of 08:12, 16 April 2014
Crystal structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with oxonate
Function
[PYRD_TRYCC] Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor. Molecular oxygen can replace fumarate in vitro.
About this Structure
2e6f is a 2 chain structure with sequence from Trycr. Full crystallographic information is available from OCA.
See Also
Reference
- Inaoka DK, Sakamoto K, Shimizu H, Shiba T, Kurisu G, Nara T, Aoki T, Kita K, Harada S. Structures of Trypanosoma cruzi dihydroorotate dehydrogenase complexed with substrates and products: atomic resolution insights into mechanisms of dihydroorotate oxidation and fumarate reduction. Biochemistry. 2008 Oct 14;47(41):10881-91. Epub 2008 Sep 23. PMID:18808149 doi:10.1021/bi800413r