1ga3: Difference between revisions
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{{STRUCTURE_1ga3| PDB=1ga3 | SCENE= }} | {{STRUCTURE_1ga3| PDB=1ga3 | SCENE= }} | ||
===NMR STRUCTURE OF INTERLEUKIN-13=== | |||
{{ABSTRACT_PUBMED_11419949}} | |||
== | ==Disease== | ||
[[http://www.uniprot.org/uniprot/IL13_HUMAN IL13_HUMAN]] Defects in IL13 may be a cause of susceptibility to allergic rhinitis (ALRH) [MIM:[http://omim.org/entry/607154 607154]]. Allergic rhinitis is a common disease of complex inheritance and is characterized by mucosal inflammation caused by allergen exposure. | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/IL13_HUMAN IL13_HUMAN]] Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses. | |||
==About this Structure== | ==About this Structure== | ||
| Line 14: | Line 16: | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:011419949</ref><references group="xtra"/> | <ref group="xtra">PMID:011419949</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Altieri, A S.]] | [[Category: Altieri, A S.]] | ||
Revision as of 16:38, 24 March 2013
NMR STRUCTURE OF INTERLEUKIN-13
Template:ABSTRACT PUBMED 11419949
Disease
[IL13_HUMAN] Defects in IL13 may be a cause of susceptibility to allergic rhinitis (ALRH) [MIM:607154]. Allergic rhinitis is a common disease of complex inheritance and is characterized by mucosal inflammation caused by allergen exposure.
Function
[IL13_HUMAN] Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses.
About this Structure
1ga3 is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.
See Also
Reference
- Eisenmesser EZ, Horita DA, Altieri AS, Byrd RA. Solution structure of interleukin-13 and insights into receptor engagement. J Mol Biol. 2001 Jun 29;310(1):231-41. PMID:11419949 doi:https://dx.doi.org/10.1006/jmbi.2001.4765
