Gelsolin: Difference between revisions

From Proteopedia
Jump to navigationJump to search
Michal Harel (talk | contribs)
No edit summary
Michal Harel (talk | contribs)
No edit summary
Line 12: Line 12:
}}
}}
-->
-->
{{STRUCTURE_2fgh|  PDB=2fgh  |  SCENE= |CAPTION=Gelsolin (GLS), [[2fgh]] }}
{{STRUCTURE_2fgh|  PDB=2fgh  |  SCENE= |CAPTION=Gelsolin (GLS) dimer complex with ATP, [[2fgh]] }}
 
 
 
 
 
 
 
 
 
 
 
 


[[Gelsolin]] (GLS) is a protein regulator of actin assembly and disassembly. The images at the top and at the right  correspond to one representative gelsolin structure, ''i.e.'' the human gelsolin ([[3ffn]]), it has <scene name='Gelsolin/Cv/2'>dimeric form</scene>. It contains 6 homologous domains S1 to S6.   
[[Gelsolin]] (GLS) is a protein regulator of actin assembly and disassembly. The images at the top and at the right  correspond to one representative gelsolin structure, ''i.e.'' the human gelsolin ([[3ffn]]), it has <scene name='Gelsolin/Cv/2'>dimeric form</scene>. It contains 6 homologous domains S1 to S6.   

Revision as of 12:09, 1 November 2012

File:3ffn.jpg

Template:STRUCTURE 2fgh







Gelsolin (GLS) is a protein regulator of actin assembly and disassembly. The images at the top and at the right correspond to one representative gelsolin structure, i.e. the human gelsolin (3ffn), it has dimeric form. It contains 6 homologous domains S1 to S6.








3D Structures of GLS

GLS

3ffn – hGLS – human
2fgh – hoGLS+ATP – horse
1d0n - hoGLS
2x1o, 1x1p, 1x1q – GLS nanobody - Llama

GLS domains S1-S3

3ffk – hGLS domains S1-S3+actin
1rgi - hoGLS domains S1-S3+actin


GLS domains S4-S6

1h1v - hGLS domains S4-S6+actin
1nph - GLS domains S4-S6+Ca – mouse


GLS domain S1

2ff3 - hGLS domain S1+N-WASP+actin
2ff6 - hGLS domain S1+Ciboulot domain 2+actin
1mdu - hGLS domain S1+chActin – chicken
1d4x - hGLS domain S1+CeActin+Mg-ATP – Caenorhabditis elegans
1esv - hGLS domain S1+rActin+latrunculin – rabbit
1eqy - hGLS domain S1+rActin
1yvn - hGLS domain S1+yActin (mutant) – yeast
1yag - hGLS domain S1+yActin
1t44 - hGLS domain S1-thymosin β-4 C-terminal fusion+rActin
1kcq – hGLS domainS1+Cd
1c0f - hGLS domain S1+DdActin+Ca-ATP - Dictyostelium discoideum
1c0g, 1dej - hGLS domain S1+DdActin (mutant)
3a5l, 3a5m, 3a5n, 3a5o - hGLS domain S1 (mutant)+DdActin (mutant)
3ci5, 3cip, 1nlv – DdGLS domain S1+actin
1nm1 - DdGLS domain S1+actin+Mg-ATP
3cjb - rGLS domain S1+rActin
3cjc - rGLS domain S1+rActin+DNAse I
1nmd - hGLS domain S1+actin+Ca+ATP


GLS C-terminal

2fh1, 2fh2, 2fh3, 2fh4 – hGLS C-terminal
1p8x - hGLS C-terminal+Ca
1p8z – hGLS fraction+rActin

Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Jaime Prilusky, Michal Harel