4joi: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4joi|  PDB=4joi  |  SCENE=  }}
===Crystal structure of the human telomeric Stn1-Ten1 complex===


The entry 4joi is ON HOLD  until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/STN1_HUMAN STN1_HUMAN]] Component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites.<ref>PMID:19854130</ref> <ref>PMID:19648609</ref>  [[http://www.uniprot.org/uniprot/TEN1L_HUMAN TEN1L_HUMAN]] Component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites.


Authors: Bryan, C., Rice, C., Harkisheimer, M., Schultz, D., Skordalakes, E.
==About this Structure==
[[4joi]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JOI OCA].  


Description: Crystal structure of the human telomeric Stn1-Ten1 complex
==Reference==
<references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Bryan, C.]]
[[Category: Harkisheimer, M.]]
[[Category: Rice, C.]]
[[Category: Schultz, D.]]
[[Category: Skordalakes, E.]]
[[Category: Dna binding protein]]
[[Category: Ob fold]]