3psx: Difference between revisions

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{{STRUCTURE_3psx|  PDB=3psx  |  SCENE=  }}  
{{STRUCTURE_3psx|  PDB=3psx  |  SCENE=  }}  
===Crystal structure of the KT2 mutant of cytochrome P450 BM3===
===Crystal structure of the KT2 mutant of cytochrome P450 BM3===
{{ABSTRACT_PUBMED_21603690}}


==Function==
==Function==
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==About this Structure==
==About this Structure==
[[3psx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_megaterium Bacillus megaterium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PSX OCA].  
[[3psx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_14581 Atcc 14581]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PSX OCA].  


==See Also==
==See Also==
*[[Cytochrome P450|Cytochrome P450]]
*[[Cytochrome P450|Cytochrome P450]]
[[Category: Bacillus megaterium]]
*[[NADPH-Cytochrome P450 Reductase|NADPH-Cytochrome P450 Reductase]]
 
==Reference==
<ref group="xtra">PMID:021603690</ref><references group="xtra"/><references/>
[[Category: Atcc 14581]]
[[Category: Unspecific monooxygenase]]
[[Category: Unspecific monooxygenase]]
[[Category: Bartlam, M.]]
[[Category: Bartlam, M.]]

Revision as of 07:40, 18 December 2013

Template:STRUCTURE 3psx

Crystal structure of the KT2 mutant of cytochrome P450 BM3

Template:ABSTRACT PUBMED 21603690

Function

[CPXB_BACME] Functions as a fatty acid monooxygenase. Catalyzes hydroxylation of medium and long-chain fatty acids at omega-1, omega-2 and omega-3 positions, with optimum chain lengths of 12-16 carbons (lauric, myristic, and palmitic acids). The reductase domain is required for electron transfer from NADP to cytochrome P450.

About this Structure

3psx is a 2 chain structure with sequence from Atcc 14581. Full crystallographic information is available from OCA.

See Also

Reference

  1. Whitehouse CJ, Yang W, Yorke JA, Tufton HG, Ogilvie LC, Bell SG, Zhou W, Bartlam M, Rao Z, Wong LL. Structure, electronic properties and catalytic behaviour of an activity-enhancing CYP102A1 (P450(BM3)) variant. Dalton Trans. 2011 Oct 28;40(40):10383-96. doi: 10.1039/c1dt10098j. Epub 2011 May, 20. PMID:21603690 doi:https://dx.doi.org/10.1039/c1dt10098j

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