2m7f: Difference between revisions

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{{STRUCTURE_2m7f|  PDB=2m7f  |  SCENE=  }}
==The C-terminal Region of Disintegrin Modulate its 3D Conformation and Cooperate with RGD Loop in Regulating Integrins Recognitions==
===The C-terminal Region of Disintegrin Modulate its 3D Conformation and Cooperate with RGD Loop in Regulating Integrins Recognitions===
<StructureSection load='2m7f' size='340' side='right' caption='[[2m7f]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
 
== Structural highlights ==
==Function==
<table><tr><td colspan='2'>[[2m7f]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Calloselasma_rhodostoma Calloselasma rhodostoma]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M7F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2M7F FirstGlance]. <br>
[[http://www.uniprot.org/uniprot/VM2RH_CALRH VM2RH_CALRH]] Metalloproteinase rhodostoxin: snake venom metalloproteinase that impairs hemostasis in the envenomed animal (By similarity).  Disintegrin rhodostomin: inhibit platelet aggregation induced by ADP, thrombin, platelet-activating factor and collagen. Acts by inhibiting fibrinogen interaction with platelet receptors GPIIb/GPIIIa (ITGA2B/ITGB3).
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2pji|2pji]], [[2m75|2m75]], [[2m7h|2m7h]]</td></tr>
 
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RHOD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=8717 Calloselasma rhodostoma])</td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2m7f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m7f OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2m7f RCSB], [http://www.ebi.ac.uk/pdbsum/2m7f PDBsum]</span></td></tr>
[[2m7f]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Calloselasma_rhodostoma Calloselasma rhodostoma]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M7F OCA].  
</table>
__TOC__
</StructureSection>
[[Category: Calloselasma rhodostoma]]
[[Category: Calloselasma rhodostoma]]
[[Category: Chang, Y.]]
[[Category: Chang, Y]]
[[Category: Chuang, W.]]
[[Category: Chuang, W]]
[[Category: C-terminal region mutation]]
[[Category: C-terminal region mutation]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Rgd motif]]
[[Category: Rgd motif]]
[[Category: Rhodostomin mutant protein]]
[[Category: Rhodostomin mutant protein]]

Revision as of 12:26, 18 December 2014

The C-terminal Region of Disintegrin Modulate its 3D Conformation and Cooperate with RGD Loop in Regulating Integrins Recognitions

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