CD1: Difference between revisions

Line 1:

'''CD1''' (or '''Cluster of Differentiation 1''') is related to class I MHC molecules. CD1 is expressed on the surface of antigen presenting cells and presents lipid antigens to T cells. There are 3 groups of CD1 differing in their lipid anchoring. Group 1 contains CD1a, CD1b and CD1c. Group 2 contains CD1d. Group 3 contains CD1e. CD1 structure is comprised of a heavy chain with a1, a2 and a3 domains which is non-covalently associated with β-microglobulin. CD1 contains a larger and deeper antigen binding groove than class I MHC molecules.

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

Revision as of 09:58, 26 June 2013 view source Michal Harel (talk \| contribs) 32,820 edits No edit summary ← Older edit		Revision as of 11:06, 4 December 2013 view source Michal Harel (talk \| contribs) 32,820 edits No edit summary Newer edit →
Line 1:		Line 1:
	<StructureSection load='3ilp' size='350' side='right' caption='Structure of mouse CD1 extracellular domain (grey) containing β-microglobulin (~~yellow~~) complex with glycolipid (PDB entry [[~~3lip~~]])' scene=''>		<StructureSection load='3ilp' size='350' side='right' caption='Structure of mouse CD1 extracellular domain (grey) containing β-microglobulin (green) complex with glycolipid (PDB entry [[3ilp]])' scene=''>

	'''CD1''' (or '''Cluster of Differentiation 1''') is related to class I MHC molecules. CD1 is expressed on the surface of antigen presenting cells and presents lipid antigens to T cells. There are 3 groups of CD1 differing in their lipid anchoring. Group 1 contains CD1a, CD1b and CD1c. Group 2 contains CD1d. Group 3 contains CD1e. CD1 structure is comprised of a heavy chain with a1, a2 and a3 domains which is non-covalently associated with β-microglobulin. CD1 contains a larger and deeper antigen binding groove than class I MHC molecules.		'''CD1''' (or '''Cluster of Differentiation 1''') is related to class I MHC molecules. CD1 is expressed on the surface of antigen presenting cells and presents lipid antigens to T cells. There are 3 groups of CD1 differing in their lipid anchoring. Group 1 contains CD1a, CD1b and CD1c. Group 2 contains CD1d. Group 3 contains CD1e. CD1 structure is comprised of a heavy chain with a1, a2 and a3 domains which is non-covalently associated with β-microglobulin. CD1 contains a larger and deeper antigen binding groove than class I MHC molecules.