3wcy: Difference between revisions
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==Murine Ifnar1 in complex with interferon-beta== | |||
=== | <StructureSection load='3wcy' size='340' side='right' caption='[[3wcy]], [[Resolution|resolution]] 2.90Å' scene=''> | ||
== Structural highlights == | |||
==Function== | <table><tr><td colspan='2'>[[3wcy]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WCY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WCY FirstGlance]. <br> | ||
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3s98|3s98]], [[3se3|3se3]], [[3se4|3se4]], [[1wu3|1wu3]], [[1au1|1au1]]</td></tr> | |||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Ifar, Ifnar, Ifnar1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus]), Ifb, Ifnb, Ifnb1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wcy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wcy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wcy RCSB], [http://www.ebi.ac.uk/pdbsum/3wcy PDBsum]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/INAR1_MOUSE INAR1_MOUSE]] Associates with IFNAR2 to form the type I interferon receptor. Receptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta-subunits themselves. [[http://www.uniprot.org/uniprot/IFNB_MOUSE IFNB_MOUSE]] Has antiviral, antibacterial and anticancer activities. | [[http://www.uniprot.org/uniprot/INAR1_MOUSE INAR1_MOUSE]] Associates with IFNAR2 to form the type I interferon receptor. Receptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha- and beta-subunits themselves. [[http://www.uniprot.org/uniprot/IFNB_MOUSE IFNB_MOUSE]] Has antiviral, antibacterial and anticancer activities. | ||
== | ==See Also== | ||
[[ | *[[Interferon receptor|Interferon receptor]] | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Hertzog, P J | [[Category: Hertzog, P J]] | ||
[[Category: Rossjohn, J | [[Category: Rossjohn, J]] | ||
[[Category: Vivian, J P | [[Category: Vivian, J P]] | ||
[[Category: Weerd, N A.de | [[Category: Weerd, N A.de]] | ||
[[Category: Cytokine receptor]] | [[Category: Cytokine receptor]] | ||
[[Category: Cytokine receptor-cytokine complex]] | [[Category: Cytokine receptor-cytokine complex]] | ||
Revision as of 01:28, 25 December 2014
Murine Ifnar1 in complex with interferon-beta
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