4ly9: Difference between revisions
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{{STRUCTURE_4ly9| PDB=4ly9 | SCENE= }} | |||
===Human GKRP complexed to AMG-1694 [(2R)-1,1,1-trifluoro-2-{4-[(2S)-2-{[(3S)-3-methylmorpholin-4-yl]methyl}-4-(thiophen-2-ylsulfonyl)piperazin-1-yl]phenyl}propan-2-ol] and sorbitol-6-phosphate=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/GCKR_HUMAN GCKR_HUMAN]] Inhibits glucokinase by forming an inactive complex with this enzyme. | |||
==About this Structure== | |||
[[4ly9]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LY9 OCA]. | |||
[[Category: Jordan, S R.]] | |||
[[Category: Carbohydrate binding protein]] | |||
[[Category: Disruptor ligand complex]] | |||
[[Category: Gkrp binds to gk]] | |||
[[Category: Liver]] | |||
[[Category: Regulatory protein]] | |||
[[Category: Sis domain]] | |||
Revision as of 13:45, 20 November 2013
Human GKRP complexed to AMG-1694 [(2R)-1,1,1-trifluoro-2-{4-[(2S)-2-{[(3S)-3-methylmorpholin-4-yl]methyl}-4-(thiophen-2-ylsulfonyl)piperazin-1-yl]phenyl}propan-2-ol] and sorbitol-6-phosphate
Function
[GCKR_HUMAN] Inhibits glucokinase by forming an inactive complex with this enzyme.
About this Structure
4ly9 is a 2 chain structure. Full crystallographic information is available from OCA.