4kfg: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,097 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,097 edits
No edit summary
Line 1: Line 1:
{{STRUCTURE_4kfg|  PDB=4kfg  |  SCENE=  }}
==The DNA Gyrase B ATP binding domain of Escherichia coli in complex with a small molecule inhibitor.==
===The DNA Gyrase B ATP binding domain of Escherichia coli in complex with a small molecule inhibitor.===
<StructureSection load='4kfg' size='340' side='right' caption='[[4kfg]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4kfg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KFG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KFG FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DOO:6-FLUORO-4-[(3AR,6AR)-HEXAHYDROPYRROLO[3,4-B]PYRROL-5(1H)-YL]-N-METHYL-2-[(2-METHYLPYRIMIDIN-5-YL)OXY]-9H-PYRIMIDO[4,5-B]INDOL-8-AMINE'>DOO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4k4o|4k4o]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">acrB, himB, hisU, nalC, parA, pcbA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_topoisomerase_(ATP-hydrolyzing) DNA topoisomerase (ATP-hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.3 5.99.1.3] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kfg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kfg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4kfg RCSB], [http://www.ebi.ac.uk/pdbsum/4kfg PDBsum]</span></td></tr>
</table>


==Function==
==See Also==
[[http://www.uniprot.org/uniprot/GYRB_ECOLI GYRB_ECOLI]] DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings.<ref>PMID:12051843</ref> <ref>PMID:18642932</ref> <ref>PMID:20675723</ref> 
*[[Gyrase|Gyrase]]
 
__TOC__
==About this Structure==
</StructureSection>
[[4kfg]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KFG OCA].
[[Category: Ecoli]]
 
[[Category: Akers-Rodriguez, S]]
==Reference==
[[Category: Bensen, D C]]
<references group="xtra"/><references/>
[[Category: Lam, T]]
[[Category: Akers-Rodriguez, S.]]
[[Category: Tari, L W]]
[[Category: Bensen, D C.]]
[[Category: Lam, T.]]
[[Category: Tari, L W.]]
[[Category: Atp-binding]]
[[Category: Atp-binding]]
[[Category: Atp-binding domain]]
[[Category: Atp-binding domain]]

Revision as of 16:23, 21 December 2014

The DNA Gyrase B ATP binding domain of Escherichia coli in complex with a small molecule inhibitor.

4kfg, resolution 1.60Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "https://proteopedia.org/index.php?title=4kfg&oldid=2146850"