3c1t: Difference between revisions

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New page: left|200px<br /><applet load="3c1t" size="350" color="white" frame="true" align="right" spinBox="true" caption="3c1t, resolution 2.252Å" /> '''Binding of two subs...
 
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[[Image:3c1t.jpg|left|200px]]<br /><applet load="3c1t" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:3c1t.jpg|left|200px]]
caption="3c1t, resolution 2.252&Aring;" />
 
'''Binding of two substrate analogue molecules to dihydroflavonol 4-reductase alters the functional geometry of the catalytic site'''<br />
{{Structure
|PDB= 3c1t |SIZE=350|CAPTION= <scene name='initialview01'>3c1t</scene>, resolution 2.252&Aring;
|SITE= <scene name='pdbsite=AC1:Nap+Binding+Site+For+Residue+A+340'>AC1</scene>, <scene name='pdbsite=AC2:Myc+Binding+Site+For+Residue+A+341'>AC2</scene>, <scene name='pdbsite=AC3:Myc+Binding+Site+For+Residue+A+342'>AC3</scene>, <scene name='pdbsite=AC4:Nap+Binding+Site+For+Residue+B+340'>AC4</scene>, <scene name='pdbsite=AC5:Myc+Binding+Site+For+Residue+B+341'>AC5</scene>, <scene name='pdbsite=AC6:Myc+Binding+Site+For+Residue+B+342'>AC6</scene>, <scene name='pdbsite=AC7:Nap+Binding+Site+For+Residue+C+340'>AC7</scene>, <scene name='pdbsite=AC8:Myc+Binding+Site+For+Residue+C+341'>AC8</scene>, <scene name='pdbsite=AC9:Myc+Binding+Site+For+Residue+C+342'>AC9</scene>, <scene name='pdbsite=BC1:Nap+Binding+Site+For+Residue+D+340'>BC1</scene>, <scene name='pdbsite=BC2:Myc+Binding+Site+For+Residue+D+341'>BC2</scene> and <scene name='pdbsite=BC3:Myc+Binding+Site+For+Residue+D+342'>BC3</scene>
|LIGAND= <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene> and <scene name='pdbligand=MYC:3,5,7-TRIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE'>MYC</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Dihydrokaempferol_4-reductase Dihydrokaempferol 4-reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.219 1.1.1.219]
|GENE= DFR1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=29760 Vitis vinifera])
}}
 
'''Binding of two substrate analogue molecules to dihydroflavonol 4-reductase alters the functional geometry of the catalytic site'''
 


==About this Structure==
==About this Structure==
3C1T is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Vitis_vinifera Vitis vinifera] with <scene name='pdbligand=NAP:'>NAP</scene> and <scene name='pdbligand=MYC:'>MYC</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Dihydrokaempferol_4-reductase Dihydrokaempferol 4-reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.219 1.1.1.219] Known structural/functional Sites: <scene name='pdbsite=AC1:Nap+Binding+Site+For+Residue+A+340'>AC1</scene>, <scene name='pdbsite=AC2:Myc+Binding+Site+For+Residue+A+341'>AC2</scene>, <scene name='pdbsite=AC3:Myc+Binding+Site+For+Residue+A+342'>AC3</scene>, <scene name='pdbsite=AC4:Nap+Binding+Site+For+Residue+B+340'>AC4</scene>, <scene name='pdbsite=AC5:Myc+Binding+Site+For+Residue+B+341'>AC5</scene>, <scene name='pdbsite=AC6:Myc+Binding+Site+For+Residue+B+342'>AC6</scene>, <scene name='pdbsite=AC7:Nap+Binding+Site+For+Residue+C+340'>AC7</scene>, <scene name='pdbsite=AC8:Myc+Binding+Site+For+Residue+C+341'>AC8</scene>, <scene name='pdbsite=AC9:Myc+Binding+Site+For+Residue+C+342'>AC9</scene>, <scene name='pdbsite=BC1:Nap+Binding+Site+For+Residue+D+340'>BC1</scene>, <scene name='pdbsite=BC2:Myc+Binding+Site+For+Residue+D+341'>BC2</scene> and <scene name='pdbsite=BC3:Myc+Binding+Site+For+Residue+D+342'>BC3</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C1T OCA].  
3C1T is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Vitis_vinifera Vitis vinifera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3C1T OCA].  
[[Category: Dihydrokaempferol 4-reductase]]
[[Category: Dihydrokaempferol 4-reductase]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: MYC]]
[[Category: MYC]]
[[Category: NAP]]
[[Category: NAP]]
[[Category: flavonoids]]
[[Category: flavonoid]]
[[Category: oxidoreductase]]
[[Category: oxidoreductase]]
[[Category: rossmann fold]]
[[Category: rossmann fold]]
[[Category: short chain dehydrogenase reductase]]
[[Category: short chain dehydrogenase reductase]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 19:08:13 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 19:02:13 2008''
Retrieved from "https://proteopedia.org/3c1t"