GTP-binding protein: Difference between revisions

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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
{{#tree:id=OrganizedByTopic|openlevels=0|


===GTP-binding protein===
*GTP-binding protein


[[3r7w]], [[4arz]] – yGtr1 + Gtr2 – yeast<br />
**[[3r7w]], [[4arz]] – yGtr1 + Gtr2 – yeast<br />
[[2eki]] – hGBP TGS domain – NMR - human<br />
**[[2eki]] – hGBP TGS domain – NMR - human<br />
[[3kxk]], [[3kxl]] – SsHflx (mutant) - ''Sulfolobus solfataricus''<br />
**[[3kxk]], [[3kxl]] – SsHflx (mutant) - ''Sulfolobus solfataricus''<br />
[[2qtf]] – SsHflx<br />
**[[2qtf]] – SsHflx<br />
[[1ega]] – EcERA – ''Escherichia coli''<br />
**[[1ega]] – EcERA – ''Escherichia coli''<br />
[[2dyk]] – TtEngA N terminal – ''Thermus thermophilus'' - Cryo EM<br />
**[[2dyk]] – TtEngA N terminal – ''Thermus thermophilus'' - Cryo EM<br />
[[3cb4]] - EcLepA<br />
**[[3cb4]] - EcLepA<br />
[[2ywe]] – AaLepA<br />
**[[2ywe]] – AaLepA<br />
[[1sul]] – BsYsxC - ''Bacillus subtilis''<br />
**[[1sul]] – BsYsxC - ''Bacillus subtilis''<br />
[[2dwq]] – TtYchF<br />
**[[2dwq]] – TtYchF<br />
[[1udx]] – TtObg<br />
**[[1udx]] – TtObg<br />
[[1wxq]] – GBP – ''Pyrococcus horikoshii''<br />
**[[1wxq]] – GBP – ''Pyrococcus horikoshii''<br />
[[1yr6]] - PaGBP – ''Pyrococcus abyssi''<br />
**[[1yr6]] - PaGBP – ''Pyrococcus abyssi''<br />
[[1ni3]] – YchF – ''Schizosaccharomyces pombe''
**[[1ni3]] – YchF – ''Schizosaccharomyces pombe''


''GTP-binding protein complex with nucleotide''
*''GTP-binding protein complex with nucleotide''


[[2nzj]] – hRem1 + GDP<br />  
**[[2nzj]] – hRem1 + GDP<br />  
[[3cbq]] – hRem2 + GDP<br />
**[[3cbq]] – hRem2 + GDP<br />
[[3q85]] – hRem2 G domain + GTP analog<br />
**[[3q85]] – hRem2 G domain + GTP analog<br />
[[2cjw]], [[2ht6]], [[2g3y]] – hGem G domain + GDP<br />
**[[2cjw]], [[2ht6]], [[2g3y]] – hGem G domain + GDP<br />
[[4aii]] - rRem2 G domain + GDP - rat<br />
**[[4aii]] - rRem2 G domain + GDP - rat<br />
[[2ohf]] – hOla1 + AMP-PCP<br />
**[[2ohf]] – hOla1 + AMP-PCP<br />
[[1xtq]] – hRheB + GDP<br />
**[[1xtq]] – hRheB + GDP<br />
[[1xts]] - hRheB + GTP<br />
**[[1xts]] - hRheB + GTP<br />
[[1xtr]] - hRheB + GPPNHP<br />
**[[1xtr]] - hRheB + GPPNHP<br />
[[3sea]] - hRheB + GDP + GNP<br />
**[[3sea]] - hRheB + GDP + GNP<br />
[[1e0a]] – hGBP (mutant) + GIP<br />
**[[1e0a]] – hGBP (mutant) + GIP<br />
[[2b8w]], [[2d4h]] – hGBP N terminal + GMP<br />
**[[2b8w]], [[2d4h]] – hGBP N terminal + GMP<br />
[[2b92]] - hGBP N terminal + GDP<br />
**[[2b92]] - hGBP N terminal + GDP<br />
[[2bc9]] - hGBP N terminal + GPPNHP<br />
**[[2bc9]] - hGBP N terminal + GPPNHP<br />
[[1yr7]], [[1yr8]] – PaGBP + GTP<br />
**[[1yr7]], [[1yr8]] – PaGBP + GTP<br />
[[1yr9]], [[1yra]], [[1yrb]], [[2oxr]] – PaGBP + GDP<br />
**[[1yr9]], [[1yra]], [[1yrb]], [[2oxr]] – PaGBP + GDP<br />
[[3kxi]], [[2qth]] – SsHflx + GDP<br />
**[[3kxi]], [[2qth]] – SsHflx + GDP<br />
[[3ieu]] – EcERA + GDP <br />
**[[3ieu]] – EcERA + GDP <br />
[[3iev]] – AaERA + RNA + Mg-GNP – ''Aquifex aeolicus''<br />
**[[3iev]] – AaERA + RNA + Mg-GNP – ''Aquifex aeolicus''<br />
[[1x1l]] – TtERA + RNA – Cryo EM<br />
**[[1x1l]] – TtERA + RNA – Cryo EM<br />
[[2ywf]] – AaLepA + GMP-PNP<br />
**[[2ywf]] – AaLepA + GMP-PNP<br />
[[2ywg]] - AaLepA + GTP<br />
**[[2ywg]] - AaLepA + GTP<br />
[[2ywh]] - AaLepA + GDP<br />
**[[2ywh]] - AaLepA + GDP<br />
[[1yzn]] – yPt1 + GPPNHP<br />
**[[1yzn]] – yPt1 + GPPNHP<br />
[[1ky2]] – yPt7 + GPPNHP<br />
**[[1ky2]] – yPt7 + GPPNHP<br />
[[1ky3]] – yPt7 + GDP<br />
**[[1ky3]] – yPt7 + GDP<br />
[[3rwm]], [[3rwo]] – yPt32 + GPPNHP<br />
**[[3rwm]], [[3rwo]] – yPt32 + GPPNHP<br />
[[1ek0]] – yPt51 + GPPNHP<br />
**[[1ek0]] – yPt51 + GPPNHP<br />
[[2hjg]], [[4dcs]], [[4dct]], [[4dcu]], [[4dcv]] – BsEngA + GDP<br />
**[[2hjg]], [[4dcs]], [[4dct]], [[4dcu]], [[4dcv]] – BsEngA + GDP<br />
[[1svi]] – BsYsxC + GDP<br />
**[[1svi]] – BsYsxC + GDP<br />
[[1svw]] – BsYsxC + GMPPNP<br />
**[[1svw]] – BsYsxC + GMPPNP<br />
[[1lnz]] – BsObg + GTP<br />
**[[1lnz]] – BsObg + GTP<br />
[[2dby]] – TtYchF + GDP<br />
**[[2dby]] – TtYchF + GDP<br />
[[1wf3]] – Tt1341 + GNP<br />
**[[1wf3]] – Tt1341 + GNP<br />
[[2gao]] - hSar1A + GDP<br />
**[[2gao]] - hSar1A + GDP<br />
[[2fa9]] – ChSar1B (mutant) + GDP – Chinese hamster<br />
**[[2fa9]] – ChSar1B (mutant) + GDP – Chinese hamster<br />
[[2fmx]] - ChSar1B + GDP<br />
**[[2fmx]] - ChSar1B + GDP<br />


''GTP-binding protein complex with protein''
*''GTP-binding protein complex with protein''


[[1x18]] – TtERA + RNA + RPS2 + RPS7 + RPS11 + RPS18 – Cryo EM<br />
**[[1x18]] – TtERA + RNA + RPS2 + RPS7 + RPS11 + RPS18 – Cryo EM<br />
[[3deg]] – EcLepA + A-tRNA + P-tRNA + RPS12 + RPL11 – Cryo EM<br />
**[[3deg]] – EcLepA + A-tRNA + P-tRNA + RPS12 + RPL11 – Cryo EM<br />
[[3cue]] – yPt1 + transport protein subunits<br />
**[[3cue]] – yPt1 + transport protein subunits<br />
[[2bcg]], [[1ukv]] - yPt1 + secretory pathway GDP-dissociation inhibitor<br />
**[[2bcg]], [[1ukv]] - yPt1 + secretory pathway GDP-dissociation inhibitor<br />
[[3cpj]] – yPt31 + Rab GDP-dissociation inhibitor<br />
**[[3cpj]] – yPt31 + Rab GDP-dissociation inhibitor<br />
[[1m2o]] – ySar1 + protein transport protein sec23<br />
**[[1m2o]] – ySar1 + protein transport protein sec23<br />
[[3syn]] – BsFlhf + ATP-binding protein<br />
**[[3syn]] – BsFlhf + ATP-binding protein<br />


''G protein bound to a G protein-coupled receptor''
*''G protein bound to a G protein-coupled receptor''


[[3sn6]] - human β-2 adrenergic receptor + cameloid antibody fragment bound by guanine nucleotide-binding protein G. '''This is the first structure of an activated [[G protein-coupled receptor]] in a complex with its G protein.'''
**[[3sn6]] - human β-2 adrenergic receptor + cameloid antibody fragment bound by guanine nucleotide-binding protein G. '''This is the first structure of an activated [[G protein-coupled receptor]] in a complex with its G protein.'''


===Ras-related GTP-binding protein===
*Ras-related GTP-binding protein


[[3llu]] – hC nucleotide-binding domain<br />
**[[3llu]] – hC nucleotide-binding domain<br />


''Ras-related GTP-binding protein complex with nucleotide''
*''Ras-related GTP-binding protein complex with nucleotide''


[[2l0x]] – rRheb + GDP <br />
**[[2l0x]] – rRheb + GDP <br />
[[2gjs]] – hRad1 + GDP<br />
**[[2gjs]] – hRad1 + GDP<br />
[[3q72]], [[3q7p]], [[3q7q]] – hRad G-domain + GTP analog<br />
**[[3q72]], [[3q7p]], [[3q7q]] – hRad G-domain + GTP analog<br />
[[2dpx]] – hRad GTPase domain<br />
**[[2dpx]] – hRad GTPase domain<br />
[[2gf0]] – hDiRas1 + GDP<br />
**[[2gf0]] – hDiRas1 + GDP<br />
[[2erx]] – hDiRas2 + Pi + GDP<br />
**[[2erx]] – hDiRas2 + Pi + GDP<br />
[[1x3s]] – hRab-18 + GPPNHP<br />
**[[1x3s]] – hRab-18 + GPPNHP<br />
[[1yu9]] - hRab-4A + GPPNHP<br />
**[[1yu9]] - hRab-4A + GPPNHP<br />
[[2atx]] – hTc10 + GPPNHP<br />
**[[2atx]] – hTc10 + GPPNHP<br />
[[1g16]] – ySec4 + GDP<br />
**[[1g16]] – ySec4 + GDP<br />
[[1g17]] - ySec4 + GIP<br />
**[[1g17]] - ySec4 + GIP<br />


''Ras-related GTP-binding protein complex with protein''
*''Ras-related GTP-binding protein complex with protein''


[[3kuc]] – hRap-1A + proto oncogene Ser/Thr protein kinase<br />
**[[3kuc]] – hRap-1A + proto oncogene Ser/Thr protein kinase<br />
[[3cf6]] - hRap-1A + Rap guanine nucleotide exchange factor 4<br />
**[[3cf6]] - hRap-1A + Rap guanine nucleotide exchange factor 4<br />
[[3brw]] - hRap-1B + Rap GTPase-activating protein<br />
**[[3brw]] - hRap-1B + Rap GTPase-activating protein<br />
[[1z0k]] – hRab-4 + rabenosyn-5<br />
**[[1z0k]] – hRab-4 + rabenosyn-5<br />
[[3tw8]] – hRab-1C + DENND<br />
**[[3tw8]] – hRab-1C + DENND<br />


===Interferon-induced GTP-binding protein===
*Interferon-induced GTP-binding protein


[[3ljb]] – hMx1 stalk region<br />
**[[3ljb]] – hMx1 stalk region<br />
[[3szr]] – hMx1 residues 33-662<br />
**[[3szr]] – hMx1 residues 33-662<br />
[[3zys]] – hMx1 + dynamin-1<br />
**[[3zys]] – hMx1 + dynamin-1<br />


===Rho-related GTP-binding protein===
*Rho-related GTP-binding protein


[[2j1l]] – hRhoD
**[[2j1l]] – hRhoD


''Rho-related GTP-binding protein complex with nucleotide''
*''Rho-related GTP-binding protein complex with nucleotide''


[[2cls]] – hRho6 + GTP<br />
**[[2cls]] – hRho6 + GTP<br />
[[2fv8]] - hRhoB + GDP<br />
**[[2fv8]] - hRhoB + GDP<br />
[[2gcn]] – hRhoC + GDP<br />
**[[2gcn]] – hRhoC + GDP<br />
[[2gco]] – hRhoC + GPPNHP<br />
**[[2gco]] – hRhoC + GPPNHP<br />
[[1z2c]] - hRhoC (mutant) + GMPPNP<br />
**[[1z2c]] - hRhoC (mutant) + GMPPNP<br />
[[2gcp]] – hRhoC + GSP<br />
**[[2gcp]] – hRhoC + GSP<br />
[[1m7b]] - hRhoE + GTP<br />
**[[1m7b]] - hRhoE + GTP<br />
[[1gwn]] - RhoE + GTP - mouse<br />
**[[1gwn]] - RhoE + GTP - mouse<br />
[[1a4r]] - hCdc42 (mutant) + GDP<br />
**[[1a4r]] - hCdc42 (mutant) + GDP<br />
[[1an0]] - hCdc42 + GDP<br />
**[[1an0]] - hCdc42 + GDP<br />
[[2qrz]] - hCdc42 + GCP<br />
**[[2qrz]] - hCdc42 + GCP<br />


''Rho-related GTP-binding protein complex with protein''
*''Rho-related GTP-binding protein complex with protein''


[[2v55]] – hRhoE + Rho-associated protein kinase<br />
**[[2v55]] – hRhoE + Rho-associated protein kinase<br />
[[3q3j]] – hRho6 + plexin-A2 nucleotide-binding domain<br />
**[[3q3j]] – hRho6 + plexin-A2 nucleotide-binding domain<br />
[[2rex]] – hRho6 + plexin-B1<br />
**[[2rex]] – hRho6 + plexin-B1<br />
[[1cc0]] – hRhoA + GDP-dissociation inhibitor + GDP<br />
**[[1cc0]] – hRhoA + GDP-dissociation inhibitor + GDP<br />
[[3a58]] – yRho1 (mutant) + exocyst complex component Sec3<br />
**[[3a58]] – yRho1 (mutant) + exocyst complex component Sec3<br />
[[1gzs]] – Cdc42 + guanine nucleotide exchange factor – ''Salmonella typhimurium''<br />
**[[1gzs]] – Cdc42 + guanine nucleotide exchange factor – ''Salmonella typhimurium''<br />
[[2kb0]] - hCdc42 (mutant)<br />
**[[2kb0]] - hCdc42 (mutant)<br />
[[1kz7]] - hCdc42 + guanine nucleotide exchange factor<br />
**[[1kz7]] - hCdc42 + guanine nucleotide exchange factor<br />
[[1kzg]] - hCdc42 (mutant) + guanine nucleotide exchange factor (mutant)<br />
**[[1kzg]] - hCdc42 (mutant) + guanine nucleotide exchange factor (mutant)<br />
[[2dfk]] – hCdc42 + collybistin II<br />
**[[2dfk]] – hCdc42 + collybistin II<br />
[[2wm9]], [[2wmn]], [[2wmo]] - hCdc42 + DOCK9<br />
**[[2wm9]], [[2wmn]], [[2wmo]] - hCdc42 + DOCK9<br />
[[3eg5]] - hCdc42 + protein diaphanous homolog 1 + GMPPNP<br />
**[[3eg5]] - hCdc42 + protein diaphanous homolog 1 + GMPPNP<br />
[[3gcg]] - hCdc42 + MAP<br />
**[[3gcg]] - hCdc42 + MAP<br />
[[3n3v]] - hCdc42 + AMP-protein transferase<br />
**[[3n3v]] - hCdc42 + AMP-protein transferase<br />
[[1nf3]] - hCdc42 + Par6<br />
**[[1nf3]] - hCdc42 + Par6<br />
[[2ase]] - hCdc42 (mutant) - NMR<br />
**[[2ase]] - hCdc42 (mutant) - NMR<br />
[[1ki1]] – hCdc42 + intersectin long form<br />
**[[1ki1]] – hCdc42 + intersectin long form<br />
[[1ees]] – hCdc42 + MapK3 peptide - NMR<br />
**[[1ees]] – hCdc42 + MapK3 peptide - NMR<br />
[[1doa]] - hCdc42 + GDP-dissociation inhibitor<br />
**[[1doa]] - hCdc42 + GDP-dissociation inhibitor<br />
[[2ngr]] – hCdc42 + GTPase-activating protein C terminal + GDP<br />
**[[2ngr]] – hCdc42 + GTPase-activating protein C terminal + GDP<br />
[[1am4]] – hCdc42 + GTPase-activating protein rhoGAP + GNP<br />
**[[1am4]] – hCdc42 + GTPase-activating protein rhoGAP + GNP<br />
[[1grn]] – hCdc42 + GTPase-activating protein rhoGAP + GDP<br />
**[[1grn]] – hCdc42 + GTPase-activating protein rhoGAP + GDP<br />
[[1cf4]] – hCdc42 (mutant) + ACK GTPase-binding domain + GNP - NMR<br />
**[[1cf4]] – hCdc42 (mutant) + ACK GTPase-binding domain + GNP - NMR<br />
[[1cee]] – hCdc42 + WASP GTPase-binding domain + GCP - NMR<br />
**[[1cee]] – hCdc42 + WASP GTPase-binding domain + GCP - NMR<br />
[[2odb]] – hCdc42 + PAK6 CRIB domain + GCP <br />
**[[2odb]] – hCdc42 + PAK6 CRIB domain + GCP <br />
[[3qbv]] – hCdc42 (mutant) + intersectin + GDP <br />
**[[3qbv]] – hCdc42 (mutant) + intersectin + GDP <br />
[[4did]] – hCdc42 + inositol phosphate phosphatase + GDP <br />
**[[4did]] – hCdc42 + inositol phosphate phosphatase + GDP <br />
[[1cf4]] – hCdc42 (mutant) + dedicator of cytokinesis protein 8<br />
**[[1cf4]] – hCdc42 (mutant) + dedicator of cytokinesis protein 8<br />
[[4itr]] – hCdc42 + AMP-protein transferase + GDP + AMP<br />
**[[4itr]] – hCdc42 + AMP-protein transferase + GDP + AMP<br />


===Rac-like GTP-binding protein===
*Rac-like GTP-binding protein


[[2wbl]] – AtArac2 + Rho of plant guanine nucleotide exchange factor 8 – ''Arabidopsis thaliana''<br />
**[[2wbl]] – AtArac2 + Rho of plant guanine nucleotide exchange factor 8 – ''Arabidopsis thaliana''<br />
[[3bwd]] – AtArac6<br />
**[[3bwd]] – AtArac6<br />
[[2nty]] – AtArac5 + prone8<br />
**[[2nty]] – AtArac5 + prone8<br />
[[2j0v]] – AtArac7 (mutant)<br />
**[[2j0v]] – AtArac7 (mutant)<br />


===Rab-related GTP-binding protein===
*Rab-related GTP-binding protein


[[2ys8]] – hRabJ DNAJ domain – NMR<br />
**[[2ys8]] – hRabJ DNAJ domain – NMR<br />


===Flagella-associated GTP-binding protein===
*Flagella-associated GTP-binding protein


[[2px0]] – BsFlhF + GMP-PNP <br />
**[[2px0]] – BsFlhF + GMP-PNP <br />
[[2px3]] – BsFlhF + GTP<br />
**[[2px3]] – BsFlhF + GTP<br />


===GTP-binding protein Ran===
*GTP-binding protein Ran


''Ran binary complex''
*''Ran binary complex''


[[3gj0]] – hRan + GDP<br />
**[[3gj0]] – hRan + GDP<br />
[[1i2m]] – hRan + regulator of chromosome condensation 1<br />
**[[1i2m]] – hRan + regulator of chromosome condensation 1<br />
[[1byu]] – Ran + GDP - dog<br />
**[[1byu]] – Ran + GDP - dog<br />
[[1qg2]], [[1qg4]], [[3ran]] – dRan (mutant) + GDP<br />
**[[1qg2]], [[1qg4]], [[3ran]] – dRan (mutant) + GDP<br />
[[2bku]] – dRan + importin<br />
**[[2bku]] – dRan + importin<br />


''Ran ternary complex''
*''Ran ternary complex''


[[1rrp]] – hRan + Nup358 + GTP analog<br />
**[[1rrp]] – hRan + Nup358 + GTP analog<br />
[[1qbk]] – hRan + karyopherin β2 + GTP analog<br />
**[[1qbk]] – hRan + karyopherin β2 + GTP analog<br />
[[1ibr]] – hRan + importin β1 subunit + GTP analog<br />
**[[1ibr]] – hRan + importin β1 subunit + GTP analog<br />
[[3ea5]] – hRan (mutant) + importin β1 subunit + GDP <br />
**[[3ea5]] – hRan (mutant) + importin β1 subunit + GDP <br />
[[4c0q]] - hRan (mutant) + importin 12 + GTP <br />
**[[4c0q]] - hRan (mutant) + importin 12 + GTP <br />
[[3nc1]] – hRan (mutant) + exportin 1 + GTP <br />
**[[3nc1]] – hRan (mutant) + exportin 1 + GTP <br />
[[3ch5]], [[3gj3]], [[3gj4]], [[3gj5]], [[3gj6]], [[3gj7]], [[3gj8]] – hRan + Nup153 + GDP<br />
**[[3ch5]], [[3gj3]], [[3gj4]], [[3gj5]], [[3gj6]], [[3gj7]], [[3gj8]] – hRan + Nup153 + GDP<br />
[[3w3z]] – dRan + importin β1 subunit + GTP <br />
**[[3w3z]] – dRan + importin β1 subunit + GTP <br />


''Ran quaternary complex''
*''Ran quaternary complex''


[[3gjx]] – hRan + snurportin 1 + exportin 1 + GTP <br />
**[[3gjx]] – hRan + snurportin 1 + exportin 1 + GTP <br />
[[3nby]], [[3nbz]], [[3nc0]] – hRan (mutant) + snurportin 1 + exportin 1 + GTP <br />
**[[3nby]], [[3nbz]], [[3nc0]] – hRan (mutant) + snurportin 1 + exportin 1 + GTP <br />
[[1k5d]] – hRan + Ran-specific GTPase-activating protein + Ran GTPase activating protein 1 + GTP analog<br />
**[[1k5d]] – hRan + Ran-specific GTPase-activating protein + Ran GTPase activating protein 1 + GTP analog<br />
[[1k5g]] – hRan + Ran-specific GTPase-activating protein + Ran GTPase activating protein 1 + GDP <br />
**[[1k5g]] – hRan + Ran-specific GTPase-activating protein + Ran GTPase activating protein 1 + GDP <br />
[[4gpt]], [[4gmx]], [[4hat]], [[4hb2]], [[4hb3]] – hRan + Ran-specific GTPase-activating protein + exportin 1 + GNP <br />
**[[4gpt]], [[4gmx]], [[4hat]], [[4hb2]], [[4hb3]] – hRan + Ran-specific GTPase-activating protein + exportin 1 + GNP <br />
[[4hat]], [[4hau]], [[4hav]], [[4haw]], [[4hax]], [[4hay]], [[4haz]], [[4hb0]], [[4hb4]] – hRan + Ran-specific GTPase-activating protein + exportin 1 + GNP + antibiotic<br />
**[[4hat]], [[4hau]], [[4hav]], [[4haw]], [[4hax]], [[4hay]], [[4haz]], [[4hb0]], [[4hb4]] – hRan + Ran-specific GTPase-activating protein + exportin 1 + GNP + antibiotic<br />
[[3zjy]] – hRan (mutant) + importin 13 + EIF-1A + GTP <br />
**[[3zjy]] – hRan (mutant) + importin 13 + EIF-1A + GTP <br />
[[3a6p]] – dRan + pre-microRNA + exportin 5 + peptide <br />
**[[3a6p]] – dRan + pre-microRNA + exportin 5 + peptide <br />
[[3icq]] – yRan + RNA + exportin T  <br />
**[[3icq]] – yRan + RNA + exportin T  <br />
[[3m1i]] – yRan + Ran-specific GTPase-activating protein + exportin 1 + GTP <br />
**[[3m1i]] – yRan + Ran-specific GTPase-activating protein + exportin 1 + GTP <br />


===Small GTP-binding protein===
*Small GTP-binding protein


[[2rhd]] – GBP – ''Cryptosporidium parvum''<br />
**[[2rhd]] – GBP – ''Cryptosporidium parvum''<br />
[[1yzq]] - hRab-6 + GNP<br />
**[[1yzq]] - hRab-6 + GNP<br />




[[3qq5]] – GBP – ''Thermotoga neapolitana''<br />
**[[3qq5]] – GBP – ''Thermotoga neapolitana''<br />
 
}}
==See Also==
==See Also==
* [[G protein-coupled receptor]]
* [[G protein-coupled receptor]]


[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 11:59, 26 November 2014

File:2nzj.png
Crystal Structure of GTP-binding protein Rem1 tetramer complex with nucleotide 2nzj

Template:STRUCTURE 3cbq












GTP-binding proteins or G proteins are transmitting signals outside the cell which cause changes within the cell. They act as molecular switches which are on when binding GTP and off when binding GDP. GTP-binding proteins belong to two families: heterotrimeric G proteins and small GTPases. See details on GTP-binding protein LpeD in LepA.


 
Drag the structure with the mouse to rotate
An activated G protein-coupled receptor (human β-2 adrenergic receptor in blue ) in a complex with a heterotrimeric G protein (3 subunits:reddish to orange-brown) and hormone (gold) (3sn6), resolution 3.2Å. The boundaries of the membrane in which the GPCR sits are represented in light green.


Initial scene


3D Structures of GTP-binding protein

Updated on 26-November-2014

See Also

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