3h8q: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 3: | Line 3: | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3h8q]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H8Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3H8Q FirstGlance]. <br> | <table><tr><td colspan='2'>[[3h8q]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H8Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3H8Q FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TGR, TRXR3, TXNRD3, TXNRD3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TGR, TRXR3, TXNRD3, TXNRD3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | ||
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thioredoxin-disulfide_reductase Thioredoxin-disulfide reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.9 1.8.1.9] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thioredoxin-disulfide_reductase Thioredoxin-disulfide reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.9 1.8.1.9] </span></td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3h8q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3h8q OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3h8q RCSB], [http://www.ebi.ac.uk/pdbsum/3h8q PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3h8q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3h8q OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3h8q RCSB], [http://www.ebi.ac.uk/pdbsum/3h8q PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/TRXR3_HUMAN TRXR3_HUMAN]] Displays thioredoxin reductase, glutaredoxin and glutathione reductase activities. Catalyzes disulfide bond isomerization. Promotes disulfide bond formation between GPX4 and various sperm proteins and may play a role in sperm maturation by promoting formation of sperm structural components (By similarity).[UniProtKB:Q99MD6] | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 25: | Line 27: | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Thioredoxin-disulfide reductase]] | [[Category: Thioredoxin-disulfide reductase]] | ||
[[Category: Arrowsmith, C H | [[Category: Arrowsmith, C H]] | ||
[[Category: Bountra, C | [[Category: Bountra, C]] | ||
[[Category: Chaikuad, A | [[Category: Chaikuad, A]] | ||
[[Category: Delft, F von | [[Category: Delft, F von]] | ||
[[Category: Edwards, A M | [[Category: Edwards, A M]] | ||
[[Category: Johansson, C | [[Category: Johansson, C]] | ||
[[Category: Oppermann, U | [[Category: Oppermann, U]] | ||
[[Category: Pilka, E | [[Category: Pilka, E]] | ||
[[Category: Roos, A K | [[Category: Roos, A K]] | ||
[[Category: | [[Category: Structural genomic]] | ||
[[Category: Ugochukwu, E | [[Category: Ugochukwu, E]] | ||
[[Category: Weigelt, J | [[Category: Weigelt, J]] | ||
[[Category: Yue, W | [[Category: Yue, W]] | ||
[[Category: Developmental protein]] | [[Category: Developmental protein]] | ||
[[Category: Differentiation]] | [[Category: Differentiation]] | ||
| Line 55: | Line 57: | ||
[[Category: Sgc]] | [[Category: Sgc]] | ||
[[Category: Spermatogenesis]] | [[Category: Spermatogenesis]] | ||
[[Category: Transport]] | [[Category: Transport]] | ||
Revision as of 07:50, 25 December 2014
Crystal structure of glutaredoxin domain of human thioredoxin reductase 3
| ||||||||||||
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Homo sapiens
- Thioredoxin-disulfide reductase
- Arrowsmith, C H
- Bountra, C
- Chaikuad, A
- Delft, F von
- Edwards, A M
- Johansson, C
- Oppermann, U
- Pilka, E
- Roos, A K
- Structural genomic
- Ugochukwu, E
- Weigelt, J
- Yue, W
- Developmental protein
- Differentiation
- Disulfide bond
- Electron transport
- Endoplasmic reticulum
- Fad
- Flavoprotein
- Microsome
- Nadp
- Nucleus
- Oxidoreductase
- Phosphoprotein
- Redox-active center
- Selenium
- Selenocysteine
- Sgc
- Spermatogenesis
- Transport
