2moa: Difference between revisions
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2moa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2moa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2moa RCSB], [http://www.ebi.ac.uk/pdbsum/2moa PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2moa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2moa OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2moa RCSB], [http://www.ebi.ac.uk/pdbsum/2moa PDBsum]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/CA1_CONIM CA1_CONIM]] Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. This toxin blocks mammalian neuronal nAChRs (alpha-3/beta-2 > alpha-7 > alpha-3/beta-4). Has no effect on nAChRs composed of alpha-2/beta-2, alpha-3/beta-2, alpha-4/beta-2, alpha-2/beta-4, alpha-3/beta-4, or alpha-4/beta-4 subunits. Acts voltage-independently. Is highly active against the neuromuscular receptor in frog.<ref>PMID:8206995</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Chen, S | [[Category: Chen, S]] | ||
[[Category: Heinis, C | [[Category: Heinis, C]] | ||
[[Category: Bicyclic peptide]] | [[Category: Bicyclic peptide]] | ||
[[Category: Conotoxin]] | [[Category: Conotoxin]] | ||
